School of Environmental Science and Engineering, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou, 510006, China.
School of Environment, Henan Normal University, Henan Key Laboratory for Environmental Pollution Control, Xinxiang, 453007, China.
Chemosphere. 2018 Dec;212:1067-1075. doi: 10.1016/j.chemosphere.2018.08.126. Epub 2018 Aug 29.
The widespread occurrence of non-steroidal anti-inflammatory drugs (NSAIDs) (e.g., Indomethacin) in the ambient environment has attracted growing concerns due to their potential threats to ecosystems and human health. Herein, we investigated the degradation of indomethacin (IM) by thermo-activated peroxydisulfate (PDS). The pseudo first-order rate constant (k) of degradation of IM was increased significantly with higher temperatures and PDS doses. Moreover, when the initial pH value was raised from 5 to 9 the IM degradation was initially decreased and then increased. Basic conditions were favorable for the removal of IM in the thermo-activated peroxydisulfate system. A response surface methodology based on the Box-Behnken design (BBD) was successfully employed for the optimization of the thermo-activated peroxydisulfate (PDS) system. The presence of chlorine ions manifested a dual effect on the degradation of IM, while bicarbonate and SRFA (as a NOM model) reduced it. Radical scavenging tests and electron spin resonance (ESR) revealed that the dominant oxidizing species were SO and OH at pH 9. Furthermore, the TOC removal efficiency attained 28.8% and the release of Clwas 38.5% at 60 °C within 24min, while the mineralization rate of IM were 85.5% with the PDS concentration up to 20 mM at 2 h oxidation. To summarize, thermo-activated PDS oxidation is a promising technique for the remediation of IM-contaminated water.
非甾体抗炎药（NSAIDs）（如吲哚美辛）在环境中的广泛存在引起了人们越来越多的关注，因为它们可能对生态系统和人类健康造成威胁。在此，我们研究了热激活过二硫酸盐（PDS）对吲哚美辛（IM）的降解。IM 的降解伪一级速率常数（k）随温度和 PDS 剂量的升高而显著增加。此外，当初始 pH 值从 5 升高到 9 时，IM 的降解最初降低，然后增加。碱性条件有利于热激活过二硫酸盐体系中 IM 的去除。基于 Box-Behnken 设计（BBD）的响应面法成功地用于优化热激活过二硫酸盐（PDS）体系。氯离子的存在对 IM 的降解表现出双重影响，而碳酸氢根和 SRFA（作为 NOM 模型）则降低了它。自由基捕获试验和电子自旋共振（ESR）表明，在 pH 9 时，主要的氧化物种是 SO 和 OH。此外，在 60°C 下 24 分钟内，TOC 的去除效率达到 28.8%，Cl 的释放量达到 38.5%，而在 2 小时氧化时，当 PDS 浓度高达 20 mM 时，IM 的矿化率达到 85.5%。总之，热激活过二硫酸盐氧化是一种有前途的修复 IM 污染水的技术。
