Department for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Paul Langerhans Institute Dresden of the Helmholtz Center Munich at University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Department for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
J Am Coll Cardiol. 2018 Oct 9;72(15):1829-1844. doi: 10.1016/j.jacc.2018.07.081.
The primary objective of this study was to analyze the most up-to-date evidence regarding whether and how blood sugar regulation influences cardiovascular health promotion and disease prevention by carrying out an umbrella review. Three separate, systematic literature searches identified 2,343 papers in total. Overall, 44 studies were included for data extraction and analysis. The included systematic reviews and meta-analyses published between January 1, 2016, and December 31, 2017, were of good to very good quality (median Overview Quality Assessment Questionnaire score = 17). Identified evidence suggests that cardiovascular disease (CVD) prevention services should consider regulation of blood glucose as a key target for intervention. Furthermore, the recommendations for effective intervention and service development/training described here for prevention of CVD should be adopted into evidence-based practice guidelines. Multidisciplinary teams should be formed to deliver multicomponent interventions in community-based settings. There may be substantial opportunities for integrating CVD and diabetes prevention services.
本研究的主要目的是通过伞式综述分析血糖调节对促进心血管健康和预防疾病的最新证据，包括是否以及如何影响。通过三次独立的系统文献检索，共确定了 2343 篇论文。总体而言，有 44 项研究被纳入数据提取和分析。纳入的系统综述和荟萃分析发表于 2016 年 1 月 1 日至 2017 年 12 月 31 日期间，质量较好至很好（中位数概述质量评估问卷评分=17）。已确定的证据表明，心血管疾病（CVD）预防服务应将血糖调节作为干预的关键目标。此外，这里为预防 CVD 描述的有效干预和服务发展/培训建议应纳入循证实践指南。应组建多学科团队，在社区环境中提供多组分干预措施。整合 CVD 和糖尿病预防服务可能有很大机会。
