Rocha H
Klin Monbl Augenheilkd. 1977 Jul;171(1):63-70.
After considering general preliminary immunological aspects, the author discuss the "transfer factor" of Lawrence (TF) which is one of the lymphokines that are produced by the thymus-dependent lymphocytes (LT). This factor whose nature and the probable constituent fractions are also considered, is the initiator of the cellular immunity. In immunodeficiencies, the LT should be stimulated by introducing the TF in the organism (immunotherapy). The possible use of other immunostimulating substances, which could replace the TF (levamisole BCG, thymosine), is also presented. Finally the author emphasize the large perspectives in the use of these factors in Ophthalmology: herpes, uveitis, melanoma, primary retinitis pigmentosa etc.).
在考虑了一般的初步免疫学方面之后，作者讨论了劳伦斯（Lawrence）的“转移因子”（TF），它是由胸腺依赖性淋巴细胞（LT）产生的淋巴因子之一。本文还探讨了该因子的性质及其可能的组成部分，它是细胞免疫的启动者。在免疫缺陷中，应通过向机体引入TF（免疫疗法）来刺激LT。文中还介绍了其他可替代TF的免疫刺激物质（左旋咪唑、卡介苗、胸腺素）的可能用途。最后，作者强调了这些因子在眼科应用中的广阔前景（疱疹、葡萄膜炎、黑色素瘤、原发性视网膜色素变性等）。
