类淋巴肉芽肿病样肉芽肿病，类似癌症和结节病。

Lymphomatoid granulomatosis mimicking cancer and sarcoidosis.

机构信息

Institute of Pathology and Molecular Pathology, University Hospital Zurich, Rämistrasse 100, 8091, Zürich, Switzerland.

出版信息

Ann Hematol. 2019 May;98(5):1309-1311. doi: 10.1007/s00277-018-3505-4. Epub 2018 Oct 5.

Abstract

Two cases of misdiagnoses of lymphomatoid granulomatosis are discussed here. Lymphomatoid granulomatosis is an Epstein-Barr virus-associated lymphoproliferative disorder with aggressive behavior. Due to its rarity and many presentations, delay in diagnosis and treatment is common. Its histological features including large atypical B-cells, T cell predominance, angiocentricity, necrosis, and evidence of EBV-positive cells should elicit the diagnosis of lymphomatoid granulomatosis. The settings that are described here have not yet been described in the literature.

摘要

现讨论两例误诊的淋巴组织细胞样肉芽肿病。淋巴组织细胞样肉芽肿病是一种与 EBV 相关的淋巴增生性疾病，具有侵袭性的行为。由于其罕见性和多种表现，诊断和治疗的延误很常见。其组织学特征包括大的非典型 B 细胞、T 细胞优势、血管中心性、坏死和 EBV 阳性细胞的证据，应提示诊断为淋巴组织细胞样肉芽肿病。这里描述的情况尚未在文献中描述。