Maslov L N, Tsibulnikov S Yu, Tsepokina A V, Khutornaya M V, Kutikhin A G, Tsibulnikova M R, Basalay M V, Mrochek A G
Klin Khir. 2016;94(5):395-400.
The literature data on the effectiveness of remote ischemic preconditioning (RIP) in the prevention of lung injury are contradictory. Authors of some works argue that RIP prevents lung damage during surgical interventions, the authors of other publications claim that the RIP does not protect lung against pathological processes. It is obvious that there is an urgent need for multicenter, randomized trials aimed at studying RIP protective effects against pathological processes in lung. Also required is clinical evaluation of the effectiveness of RIP in the thromboembolism of pulmonary arteries, the transplantation of the lungs and intestinal infarction. Remote preconditioning prevents the intestine injury associated with abdominal aortic aneurysm repair. Experimental data indicate that RIP has the hepatoprotective effect during ischemia and reperfusion injury of liver, septic or haemorrhagic shock. The question of whether the DIP has a protective effect during ischemia-reperfusion of the pancreas remains open.
关于远程缺血预处理（RIP）在预防肺损伤方面有效性的文献数据相互矛盾。一些研究的作者认为，RIP可预防手术干预期间的肺损伤，而其他出版物的作者则声称，RIP不能保护肺免受病理过程的影响。显然，迫切需要开展多中心随机试验，以研究RIP对肺部病理过程的保护作用。还需要对RIP在肺动脉血栓栓塞、肺移植和肠梗死方面的有效性进行临床评估。远程预处理可预防与腹主动脉瘤修复相关的肠损伤。实验数据表明，RIP在肝脏缺血再灌注损伤、感染性或出血性休克期间具有肝保护作用。关于双相缺血预处理（DIP）在胰腺缺血再灌注期间是否具有保护作用的问题仍未明确。
