Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA; Departments of Physiology and Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Cell. 2018 Oct 4;175(2):307-309. doi: 10.1016/j.cell.2018.09.025.
Life evolved in an aqueous environment, necessitating the evolution of carrier proteins to shuttle lipophilic molecules within and between cells. Sandhu et. al. (2018) report the discovery of a long-sought-after cholesterol carrier protein, named Aster, which transports cholesterol from the plasma membrane to the endoplasmic reticulum.
生命是在水环境中进化的，这就需要进化出载体蛋白，以便在细胞内和细胞间运输亲脂性分子。Sandhu 等人（2018）报告了一种长期以来备受期待的胆固醇载体蛋白的发现，该蛋白被命名为 Aster，它将胆固醇从质膜转运到内质网。
