Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, CA.
Department of Surgery, University of California, San Francisco, School of Medicine, San Francisco, CA.
Chest. 2018 Oct;154(4):e89-e92. doi: 10.1016/j.chest.2018.03.048.
Idiopathic pulmonary fibrosis is the most common idiopathic interstitial pneumonia. Prognosis is poor with a median survival <3 years. Pirfenidone is one of two US Food and Drug Administration-approved medications that slow disease progression. We describe the development of lymphadenopathy or a sarcoid-like reaction following initiation of pirfenidone, a complication not previously reported.
特发性肺纤维化是最常见的特发性间质性肺炎。预后差，中位生存期<3 年。吡非尼酮是美国食品和药物管理局批准的两种减缓疾病进展的药物之一。我们描述了在开始使用吡非尼酮后出现的淋巴结病或类肉瘤样反应，这是以前未报告过的并发症。
