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腹腔镜袖状胃切除术联合缝线加固、吻合口翻折与支撑材料对术后恶心呕吐发生率的影响:一项随机临床试验。

Incidence of postoperative nausea and vomiting after laparoscopic sleeve gastrectomy with staple line reinforcement with oversewing and staple line inversion vs buttressing material: A randomized clinical trial.

机构信息

Bariatric Surgery Unit, Centro de Excelencia para el Diagnóstico y Tratamiento de la Obesidad, Valladolid, Spain.

Centre Hospitalier Regional Universitaire Lille, France.

出版信息

Int J Surg. 2018 Nov;59:75-79. doi: 10.1016/j.ijsu.2018.09.010. Epub 2018 Oct 3.

Abstract

BACKGROUND

Postoperative nausea and vomiting are relevant complications after restrictive bariatric procedures, such as sleeve gastrectomy, mainly secondary to a drastic reduction in the gastric volume. However, other causes can be involved. The aim of this study was to determine the incidence of postoperative nausea and vomiting (PONV) after laparoscopic sleeve gastrectomy (LSG), with staple line reinforcement with oversewing vs buttressing material.

PATIENTS AND METHODS

A prospective randomized clinical trial of all the patients undergoing LSG was performed. Patients were divided into 2 groups: patients undergoing staple line inversion (Group 1) and patients undergoing staple line reinforcement with buttressing material (Group 2). Nausea and vomiting were assessed by the Postoperative Nausea and Vomiting Intensity Scale.

RESULTS

A total of 100 females were included in the study, 50 in each group. Mean operative time was 66.1 ± 11.6 min in Group 1 and 55.4 ± 9.4 in Group 2 (p < 0.001). There were no significant differences in staple line leaks and bleeds between groups. The PONV intensity score at 6 h was 316.4 in Group 1 and 77.1 in Group 2 (p < 0.001). 24 h after surgery, the PONV intensity score was 86 in Group 1 and 7.9 in Group 2 (p = 0.022).

CONCLUSION

The reinforcement with a running suture in LSG creates more PONV and increases the duration of the symptoms during the first hours after surgery, and prevents from early oral intake in a greater number of cases, when compared with the use of buttressing material as reinforcement method.

摘要

背景

袖状胃切除术等限制型减重手术后会出现恶心和呕吐等相关并发症,主要继发于胃容量的急剧减少。然而,也可能涉及其他原因。本研究旨在确定腹腔镜袖状胃切除术(LSG)中使用缝线翻修(1 组)与使用支撑材料加固吻合口(2 组)对术后恶心和呕吐(PONV)的发生率。

患者和方法

对所有接受 LSG 的患者进行前瞻性随机临床试验。患者分为 2 组:行吻合口翻修的患者(1 组)和行吻合口加固的患者(2 组)。采用术后恶心呕吐强度量表评估恶心和呕吐情况。

结果

本研究共纳入 100 例女性患者,每组 50 例。1 组的平均手术时间为 66.1±11.6 分钟,2 组为 55.4±9.4 分钟(p<0.001)。两组间吻合口漏和出血无显著差异。1 组术后 6 小时 PONV 强度评分为 316.4,2 组为 77.1(p<0.001)。术后 24 小时,1 组的 PONV 强度评分为 86,2 组为 7.9(p=0.022)。

结论

与使用支撑材料作为加固方法相比,LSG 中使用连续缝线加固会增加 PONV 的发生,并在术后最初几小时内增加症状的持续时间,从而导致更多的病例无法早期口服摄入。

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