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超细微粒对健康人群心率的影响。

Effects of the exposure to ultrafine particles on heart rate in a healthy population.

机构信息

Department of Civil and Mechanical Engineering, University of Cassino and Southern Lazio, Italy.

Department of Civil and Mechanical Engineering, University of Cassino and Southern Lazio, Italy.

出版信息

Sci Total Environ. 2019 Feb 10;650(Pt 2):2403-2410. doi: 10.1016/j.scitotenv.2018.09.385. Epub 2018 Oct 2.

DOI:10.1016/j.scitotenv.2018.09.385
PMID:30292996
Abstract

The correlation amongst exposure to ultrafine particle concentrations and heart rate in a large healthy population was investigated. The study was conducted by continuously monitoring for seven days fifty volunteers in terms of exposure to particle concentrations, heart rate and physical activity performed through portable monitors. Data were analyzed adopting a linear mixed model able to manage the obtained repeated measures and to recognize a general trend resulting from the subject-specific patterns. Results show that the short-term exposure to ultrafine particle concentrations is positively associated with the heart rate for the different physical activities of the subject investigated (laying down, sitting, standing positions). In particular, a logarithmic correlation was recognized with a sharper increase of about 4-6 bpm for a variation of the particle number concentration of 2 × 10 part/cm and a slighter effect for further increases of about 0.1-0.2 × 10 bpm/(part/cm). CAPSULE: A positive correlation can be associated between the exposure to ultrafine particles and the heart rate.

摘要

研究了在一个大型健康人群中,暴露于超细颗粒浓度与心率之间的相关性。该研究通过便携式监测器连续监测七天五十名志愿者的颗粒浓度、心率和体力活动,对其进行了监测。采用线性混合模型对数据进行分析,该模型能够处理所获得的重复测量,并识别出源于个体特定模式的总体趋势。结果表明,短期暴露于超细颗粒浓度与被调查对象的不同体力活动的心率呈正相关(躺下、坐着、站立姿势)。特别是,对于颗粒数浓度的变化为 2×10⁵ 个/cm,识别出对数相关性,心率约增加 4-6 bpm;而对于进一步增加约 0.1-0.2×10⁵ bpm/(part/cm),则影响较小。

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