Jin Liting, Wu Xinhong, Zha Li, Feng Yaojun, Xu Juan, Zheng Hongmei, Shao Jun, Zhao Minjian, Cui Xiaojiang, Giuliano Armando E, Gong Yiping
Department of Breast Surgery, Hubei Cancer Hospital, Wuhan, China.
Department of Ultrasonography, Hubei Cancer Hospital, Wuhan, China.
J Surg Oncol. 2018 Dec;118(7):1199-1204. doi: 10.1002/jso.25240. Epub 2018 Oct 7.
Surgical resection of large primary breast tumor often results in large chest wall defects. The purpose of this study is to evaluate the feasibility of using adjacent skin rotation (ASR) flap in patients with giant primary breast tumor.
A total of 26 giant primary breast tumor patients treated with ASR flap were included in this study. The postoperative conditions, including operating time, blood loss, length of hospital stay, and clinical complications were observed. Meanwhile, the information on 17 breast tumor patients treated with transverse rectus abdominis myocutaneous (TRAM) flap were collected and assigned to a control group.
The mean defect size after mastectomy was 16.7 × 13.4 cm, while the median follow-up period was 13 months after surgery. A total of 15.4% patients had developed with local complications, and one of them had more than one complication. When comparing the postoperative outcomes, statistically significant differences were found between the two groups with respect to operating time, blood loss, and length of hospital stay (P < 0.001).
ASR flap is a reliable technique for immediate reconstruction of massive chest wall defects in patients with giant primary breast tumor.
大型原发性乳腺肿瘤的手术切除常导致胸壁巨大缺损。本研究的目的是评估在原发性巨大乳腺肿瘤患者中使用邻位皮瓣旋转(ASR)皮瓣的可行性。
本研究共纳入26例接受ASR皮瓣治疗的原发性巨大乳腺肿瘤患者。观察术后情况,包括手术时间、失血量、住院时间和临床并发症。同时,收集17例接受腹直肌肌皮瓣(TRAM)皮瓣治疗的乳腺肿瘤患者的信息,并将其分配到对照组。
乳房切除术后平均缺损大小为16.7×13.4cm,术后中位随访期为13个月。共有15.4%的患者出现局部并发症,其中1例出现不止一种并发症。比较术后结果时,两组在手术时间、失血量和住院时间方面存在统计学显著差异(P<0.001)。
ASR皮瓣是原发性巨大乳腺肿瘤患者即刻重建巨大胸壁缺损的可靠技术。