糖尿病合并慢性炎症性脱髓鞘性多发性神经根神经病患者的临床分析

[The clinical analysis of diabetic patients with chronic inflammatory demyelinating polyradiculoneuropathy].

作者信息

Sun Q L, Sun A P, Fu Y, Fan D S

机构信息

Department of Neurology, Peking University Third Hospital, Beijing 100191, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2018 Oct 1;57(10):749-752. doi: 10.3760/cma.j.issn.0578-1426.2018.10.010.

DOI:10.3760/cma.j.issn.0578-1426.2018.10.010

PMID:30293336

Abstract

To explore clinical characteristics, electrophysiological findings and treatment response in diabetic patients with chronic inflammatory demyelinating polyradiculoneuropathy (DM-CIDP). Thirty-six CIDP patients were identified, 10 were DM-CIDP and 26 were non-DM-CIDP. Clinical medical records, electrophysiological data and treatment were retrospectively reviewed. DM-CIDP patients were significantly older than non-DM-CIDP patients [(56.7±10.0) years old vs. (40.4±16.9) years old, =0.001]. However, clinical characteristics and abnormalities of electrophysiological tests in both groups were comparable. DM-CIDP subjects responded to corticosteroids or intravenous immunoglobulin, thus with better prognosis.

摘要

探讨糖尿病合并慢性炎症性脱髓鞘性多发性神经根神经病（DM-CIDP）患者的临床特征、电生理表现及治疗反应。共纳入36例CIDP患者，其中10例为DM-CIDP，26例为非DM-CIDP。对患者的临床病历、电生理数据及治疗情况进行回顾性分析。DM-CIDP患者的年龄显著大于非DM-CIDP患者[（56.7±10.0）岁 vs.（40.4±16.9）岁，P =0.001]。然而，两组患者的临床特征及电生理检查异常情况具有可比性。DM-CIDP患者对皮质类固醇或静脉注射免疫球蛋白治疗有效，因此预后较好。