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社会经济地位、心房颤动与预后之间的关联:一项系统综述

Associations between socioeconomic status, atrial fibrillation, and outcomes: a systematic review.

作者信息

Lunde Elin Danielsen, Nielsen Peter Brønnum, Riahi Sam, Larsen Torben Bjerregaard, Lip Gregory Y H, Fonager Kirsten, Larsen Mogens Lytken, Joensen Albert Marni

机构信息

a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark.

b Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Faculty of Health , Aalborg University , Aalborg , Denmark.

出版信息

Expert Rev Cardiovasc Ther. 2018 Nov;16(11):857-873. doi: 10.1080/14779072.2018.1533118. Epub 2018 Oct 15.

Abstract

BACKGROUND

Atrial fibrillation (AF) is a growing epidemic and evidence of a relationship to socioeconomic status (SES) is inconsistent. We aimed to summarize the literature about SES and AF and defined two objectives: (1) To examine the association between SES and the risk of AF; (2) To examine the association between SES and AF-related outcomes in an AF-population.

METHODS

We performed a separate search for each objective in Ovid-MEDLINE and Ovid-Embase. For objective 1, the population included was healthy participants and outcome of interest was AF. For objective 2, the population included were patients with AF and outcome of interest was mortality, treatment, ablation for AF, knowledge about AF, and morbidity.

RESULTS

For objective 1, 12 studies were included. No consistent pattern for an association between SES and the risk of AF was discovered. For objective 2, 39 studies comprising 42 outcomes were included. The majority of studies showed an association between low SES and increased mortality and morbidity.

CONCLUSION

Low SES was associated with poorer outcomes when AF was present. These findings may imply that health-care professionals and policy interventions should focus on the promotion of AF-education and management among patients with AF and low SES.

摘要

背景

心房颤动(AF)的发病率呈上升趋势,而其与社会经济地位(SES)之间关系的证据并不一致。我们旨在总结关于SES与AF的文献,并确定了两个目标:(1)研究SES与AF风险之间的关联;(2)研究SES与AF患者群体中AF相关结局之间的关联。

方法

我们针对每个目标在Ovid-MEDLINE和Ovid-Embase中分别进行了检索。对于目标1,纳入的人群为健康参与者,感兴趣的结局是AF。对于目标2,纳入的人群为AF患者,感兴趣的结局是死亡率、治疗、AF消融、AF相关知识以及发病率。

结果

对于目标1,纳入了12项研究。未发现SES与AF风险之间存在一致的关联模式。对于目标2,纳入了39项研究,包含42个结局。大多数研究表明,低SES与死亡率和发病率增加之间存在关联。

结论

存在AF时,低SES与较差的结局相关。这些发现可能意味着,医疗保健专业人员和政策干预应侧重于促进对低SES的AF患者进行AF教育和管理。

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