Kaushal Brajesh, Chauhan Sandeep, Saini Kulbhushan, Bhoi Debesh, Bisoi Akshay K, Sangdup Tsering, Khan Maroof Ahmad
Department of Cardiac Anesthesiology, Cardio and Neurosciences Center, AIIMS, New Delhi, India.
Department of Cardiac Anesthesiology, Cardio and Neurosciences Center, AIIMS, New Delhi, India.
J Cardiothorac Vasc Anesth. 2019 Feb;33(2):418-425. doi: 10.1053/j.jvca.2018.08.209. Epub 2018 Aug 31.
The aim of this study was to compare the relative efficacy of ultrasound-guided serratus anterior plane block (SAPB), pectoral nerves (Pecs) II block, and intercostal nerve block (ICNB) for the management of post-thoracotomy pain in pediatric cardiac surgery.
A prospective, randomized, single-blind, comparative study.
Single-institution tertiary referral cardiac center.
The study comprised 108 children with congenital heart disease requiring surgery through a thoracotomy.
Children were allocated randomly to 1 of the 3 groups: SAPB, Pecs II, or ICNB. All participants received 3 mg/kg of 0.2% ropivacaine for ultrasound-guided block after induction of anesthesia. Postoperatively, intravenous paracetamol was used for multimodal and fentanyl was used for rescue analgesia.
A modified objective pain score (MOPS) was evaluated at 1, 2, 4, 6, 8, 10, and 12 hours post-extubation. The early mean MOPS at 1, 2, and 4 hours was similar in the 3 groups. The late mean MOPS was significantly lower in the SAPB group compared with that of the ICNB group (p < 0.001). The Pecs II group also had a lower MOPS compared with the ICNB group at 6, 8, and 10 hours (p < 0.001), but the MOPS was comparable at hour 12 (p = 0.301). The requirement for rescue fentanyl was significantly higher in ICNB group in contrast to the SAPB and Pecs II groups.
SAPB and Pecs II fascial plane blocks are equally efficacious in post-thoracotomy pain management compared with ICNB, but they have the additional benefit of being longer lasting and are as easily performed as the traditional ICNB.
本研究旨在比较超声引导下前锯肌平面阻滞(SAPB)、胸神经(Pecs)Ⅱ阻滞和肋间神经阻滞(ICNB)在小儿心脏手术开胸术后疼痛管理中的相对疗效。
一项前瞻性、随机、单盲、对照研究。
单机构三级转诊心脏中心。
本研究纳入了108例需要开胸手术的先天性心脏病患儿。
将患儿随机分为3组之一:SAPB组、PecsⅡ组或ICNB组。所有参与者在麻醉诱导后接受3mg/kg的0.2%罗哌卡因进行超声引导下阻滞。术后,静脉注射对乙酰氨基酚用于多模式镇痛,芬太尼用于补救镇痛。
在拔管后1、2、4、6、8、10和12小时评估改良的客观疼痛评分(MOPS)。3组在拔管后1、2和4小时的早期平均MOPS相似。与ICNB组相比,SAPB组在晚期的平均MOPS显著更低(p<0.001)。在6、8和10小时,PecsⅡ组的MOPS也低于ICNB组(p<0.001),但在12小时时MOPS相当(p=0.301)。与SAPB组和PecsⅡ组相比,ICNB组补救性芬太尼的需求量显著更高。
与ICNB相比,但它们具有持续时间更长的额外优势,并且与传统的ICNB一样易于实施。