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一名有子宫内膜癌病史患者结肠中的苗勒管癌肉瘤:病例报告及对可能发病机制的见解。

Mullerian carcinosarcoma in the colon of a patient with history of endometrial carcinoma: A case report and insight into possible pathogenesis.

作者信息

Hemedez Claire Anne Therese, Lomme Michele, Ruhul Quddus M

机构信息

Department of Pathology, Women and Infants Hospital, Providence, RI 02905, USA.

出版信息

Gynecol Oncol Rep. 2018 Sep 24;26:49-52. doi: 10.1016/j.gore.2018.09.003. eCollection 2018 Nov.

Abstract

•Mullerian carcinosarcoma can occur in extragenital sites.•Malignant transformation of endometriosis is common in the rectosigmoid area.•MLH1 hypermethylation has been implicated in endometriosis-associated carcinomas.•Adequate sampling is essential in determining the etiology of colonic tumors.

摘要

•苗勒管癌肉瘤可发生于生殖器外部位。

•子宫内膜异位症的恶性转化在直肠乙状结肠区域很常见。

•MLH1高甲基化与子宫内膜异位症相关的癌有关。

•足够的取材对于确定结肠肿瘤的病因至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9802/6171370/36102bf6ca48/gr1.jpg

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