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脓肿分枝杆菌:人工膝关节感染的罕见病因。

Mycobacterium abscessus: A Rare Cause of Periprosthetic Knee Joint Infection.

作者信息

Spanyer Jonathon M, Foster Scott, Thum-DiCesare Jasmine A, Kwon Young-Min M, Burke Dennis W, Nelson Sandra B

机构信息

OrthoCincy Orthopaedics and Sports Medicine, Edgewood, KY.

出版信息

Am J Orthop (Belle Mead NJ). 2018 Sep;47(9). doi: 10.12788/ajo.2018.0077.

DOI:10.12788/ajo.2018.0077
PMID:30296310
Abstract

A 61-year-old woman with a periprosthetic knee joint infection caused by Mycobacterium abscessus was successfully treated with surgical débridement, multidrug antimicrobial therapy, and staged reimplantation. To the authors' knowledge, this represents the first report of successfully treating this organism after knee arthroplasty. M. abscessus knee infections are rare, and there are no specific guidelines to inform treatment or successful treatment regimens for periprosthetic knee infections. Medical management alone was not successful in this case and hence cannot be recommended. Using a collaborative multidisciplinary approach, including surgical débridement, staged reimplantation, and multidrug antimicrobials, successful eradication of the periprosthetic joint infection caused by M. abscessus was achieved.

摘要

一名61岁女性因脓肿分枝杆菌导致人工膝关节周围感染,通过手术清创、多药联合抗菌治疗及分期再植入成功治愈。据作者所知,这是膝关节置换术后成功治疗该病原体的首例报告。脓肿分枝杆菌膝关节感染罕见,对于人工膝关节周围感染,尚无指导治疗或成功治疗方案的具体指南。该病例单纯药物治疗未成功,因此不推荐使用。采用包括手术清创、分期再植入及多药联合抗菌的多学科协作方法,成功根除了由脓肿分枝杆菌引起的人工关节周围感染。

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