Dissanayaka T D, Farrell M, Zoghi M, Egan G F, Jaberzadeh S
a Non-Invasive Brain Stimulation & Neuroplasticity Laboratory, Department of Physiotherapy, School of Primary Healthcare, Faculty of Medicine, Nursing and Health Sciences , Monash University , Melbourne , Australia.
c Monash Biomedical Imaging , Monash University , Melbourne , Australia.
Somatosens Mot Res. 2018 Sep-Dec;35(3-4):153-161. doi: 10.1080/08990220.2018.1505608. Epub 2018 Oct 9.
Supra-threshold scaling of multiple pressure-pain sensations involves delivery of varied stimulus intensities, either via stimulus-dependent or response-dependent manner, and recording of subjective pain ratings by participants. The focus of this study was to determine the intra- and inter-session reliability of pain intensity and pain unpleasantness ratings related to pressure-pain thresholds (PPTs) of just noticeable pain (JNP), weak pain (WP) and moderate pain (MP) among healthy individuals.
Fourteen healthy participants (eight women, six men) participated in three sessions of testing at varied intervals over the course of 72 h. In session one, a multiple random staircase method using hydraulic pressure algometry was used to measure PPT of JNP, WP and MP on thumbnail bed. In session 2, ratings of pain intensity and pain unpleasantness were recorded when stimuli at levels corresponding to PPT of JNP, WP and MP were repeatedly applied before and after 20 min of no intervention.
Interclass correlation coefficient (ICC) values for pain ratings of JNP, WP and MP in intra-session reliability were 0.810, 0.826 and 0.881, respectively, whereas the values were 0.817, 0.792 and 0.910, respectively, for inter-session reliability. ICC values for pain unpleasantness were also highly consistent and repeatable. Temporal summation of pain intensity and pain unpleasantness were not related to the repeated application of pressure stimuli.
The findings indicate that the pain intensity and pain unpleasantness ratings for stimuli at levels equal to the thresholds of JNP, WP and MP have good intra- and inter-session reliability.
This study showed that both pain intensity and pain unpleasantness of JNP, WP and MP have good intra- and inter-session reliability and agreement. Furthermore, the temporal summation of pain or unpleasantness is not related to repeated application of pressure stimuli.
JNP: Just noticeable pain; WP: Weak pain; MP: Moderate pain; PPTs: pressure-pain thresholds; HPA: Hydraulic pressure algometry; MRSM: multiple random staircase method.
多种压力性疼痛感觉的阈上缩放涉及通过刺激依赖或反应依赖的方式传递不同的刺激强度，并记录参与者的主观疼痛评分。本研究的重点是确定健康个体中与刚可察觉疼痛（JNP）、弱痛（WP）和中度疼痛（MP）的压力痛阈值（PPT）相关的疼痛强度和疼痛不愉快程度评分在会话内和会话间的可靠性。
14名健康参与者（8名女性，6名男性）在72小时内以不同间隔参加了三次测试。在第一次测试中，使用液压压力测痛法的多重随机阶梯法测量拇指指甲床的JNP、WP和MP的PPT。在第二次测试中，在20分钟无干预前后，当重复施加对应于JNP、WP和MP的PPT水平的刺激时，记录疼痛强度和疼痛不愉快程度的评分。
JNP、WP和MP疼痛评分在会话内可靠性的组内相关系数（ICC）值分别为0.810、0.826和0.881，而会话间可靠性的值分别为0.817、0.792和0.910。疼痛不愉快程度的ICC值也高度一致且可重复。疼痛强度和疼痛不愉快程度的时间总和与压力刺激的重复施加无关。
研究结果表明，等于JNP、WP和MP阈值水平的刺激的疼痛强度和疼痛不愉快程度评分在会话内和会话间具有良好的可靠性。
本研究表明，JNP、WP和MP的疼痛强度和疼痛不愉快程度在会话内和会话间均具有良好的可靠性和一致性。此外，疼痛或不愉快程度的时间总和与压力刺激的重复施加无关。
JNP：刚可察觉疼痛；WP：弱痛；MP：中度疼痛；PPTs：压力痛阈值；HPA：液压压力测痛法；MRSM：多重随机阶梯法
