Ivanov M T, Shevtsova Z V, Sazhchenko L A
Vopr Virusol. 1986 Nov-Dec;31(6):706-9.
The ultrastructure of coronaviruses from 46 out of 111 monkeys examined (baboons, macaques, green monkeys, langurs) was studied by negative staining in homogenates of different parts of the intestinal tract, pancreatic gland, liver, kidneys, lungs, heart, and brain. Because of marked pleomorphism of coronaviruses it is suggested that morphological variants of the viruses may be distinguished. No relationship between pleomorphism of virus particles and species differences of monkeys and their organ pathology was established. Morphological signs distinguishing simian coronaviruses from those of man were noted.
对111只接受检查的猴子(狒狒、猕猴、绿猴、叶猴)中的46只,通过对肠道、胰腺、肝脏、肾脏、肺、心脏和大脑不同部位的匀浆进行负染色,研究了冠状病毒的超微结构。由于冠状病毒具有明显的多形性,因此有人认为可以区分病毒的形态变体。未发现病毒颗粒的多形性与猴子的物种差异及其器官病理学之间存在关联。注意到了将猿猴冠状病毒与人类冠状病毒区分开来的形态学特征。