The Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
The Center for Drug Safety and Policy Research, Xi'an Jiaotong University, Xi'an, China.
PLoS One. 2018 Oct 9;13(10):e0205238. doi: 10.1371/journal.pone.0205238. eCollection 2018.
The shortage of emergency drugs in China is severe. This study aimed to characterize emergency drug shortages in China and to measure their effects.
An online questionnaire based on a literature review was sent to emergency department physicians in Chinese secondary and tertiary hospitals from November 2016 to February 2017. The survey asked physicians questions about their experiences with emergency drug shortages.
In total, 236 physicians from 29 provinces participated in the survey. According to their responses, 90.7% of the respondents experienced drug shortages during the last year. More than half of the physicians (65.7%) reported that drug shortages occurred at least once a month. Hospitals in the eastern and western regions of China had more emergency drugs in shortage than hospitals in central China, especially those with many inpatient beds (≥800). In addition, the shortage situation was more serious in secondary hospitals than in tertiary hospitals. More respondents agreed that original medicines, injections, essential medicines, medicines without alternative agents and cheap medicines were more susceptible to shortages than generics, oral medicines, nonessential medicines, medicines with alternative agents and expensive medicines, respectively. Most respondents thought that drug shortages always, often or sometimes affected patients [delayed therapy (62.6%), longer rescue and recovery times (58.9%) and higher costs (58.7%)] and physicians [inconvenience (81.0%), higher pressure (76.5%) and harm to patient-doctor relationships (72%)] and compromised hospital reputations (55.1%).
The shortage of emergency drugs in China is serious, especially in secondary hospitals located in eastern and western China. Emergency drug shortages have significant effects on patients and physicians.
中国急救药品短缺严重。本研究旨在描述中国急救药品短缺情况并评估其影响。
2016 年 11 月至 2017 年 2 月,我们采用文献回顾基础上形成的在线问卷,对中国二级和三级医院的急诊医师进行调查。问卷询问了医师有关急救药品短缺的经历。
共 236 名来自 29 个省的医师参与了调查。根据他们的回答,90.7%的受访者在过去一年中经历过药品短缺。超过一半的医师(65.7%)报告称,药品短缺每月至少发生一次。中国东部和西部地区的医院比中部地区的医院有更多的急救药品短缺,尤其是那些拥有 800 张以上住院床位的医院。此外,二级医院的短缺情况比三级医院更为严重。更多的受访者认为,与仿制药相比,原研药、注射剂、基本药物、无替代药物的药物和廉价药物更容易短缺,而不是仿制药、口服药物、非基本药物、有替代药物的药物和昂贵药物。大多数受访者认为,药品短缺总是、经常或有时会影响患者(治疗延迟 62.6%,抢救和恢复时间延长 58.9%,费用增加 58.7%)和医生(不便 81.0%,压力增加 76.5%,医患关系受损 72%),并影响医院声誉(55.1%)。
中国急救药品短缺严重,特别是在东部和西部地区的二级医院。急救药品短缺对患者和医生有重大影响。