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[用生物假体单独置换三尖瓣。关于阿比让的22例病例]

[Isolated replacement of the tricuspid valve with a bioprosthesis. Apropos of 22 cases in Abidjan].

作者信息

Chauvet J, Seka R, Mardelle T, Touze J E, Métras D, Ticolat R, Ouattara K, Coulibaly A O, Bertrand E

出版信息

Arch Mal Coeur Vaiss. 1986 Oct;79(11):1625-9.

PMID:3030216
Abstract

The authors reviewed the operative and function results of 24 isolated tricuspid valve replacements with bioprostheses in 22 patients. The patient population was young (average age 15 +/- 8 years). The surgical indication was massive tricuspid regurgitation due to chronic parietal endocarditis in 19 cases and to bacterial endocarditis in 3 cases. Tricuspid valve replacement was associated with 19 right ventricular endocardectomies, 2 direct closures of ventricular septal defects, 2 Wooler mitral valvuloplasties and 1 pericardectomy. The operative mortality was 13.5% and the secondary mortality 13.5%. Of the 16 survivors, 13 are in the NYHA Class I with no regular medical therapy. Their cardiothoracic ratio has slightly decreased. Two patients have permanent atrial fibrillation, and 12 have acquired definitive complete right bundle branch block. Eight of these patients had significant improvement of atrial and right ventricular pressures, of Yu's index and cardiac index at postoperative catheterisation. Three of the 16 patients developed progressive calcific degeneration of their bioprostheses. They are among the 6 patients who have been followed up for more than 3 years. There was no mortality at reoperation. Isolated tricuspid valve replacement by bioprosthesis was chosen despite the young age of these patients because of the disadvantages of mechanical prostheses which are associated with a much higher mortality related to incarceration and thrombosis of the prosthesis. The relatively high operative and secondary mortality in this series of isolated tricuspid valve replacement compared to mitral, aortic or micro-aortic valve replacement, is related to the gravity of the underlying causal pathology.

摘要

作者回顾了22例患者接受24次生物瓣单独三尖瓣置换术的手术及功能结果。患者群体较为年轻(平均年龄15±8岁)。手术指征为:19例因慢性心内膜炎导致大量三尖瓣反流,3例因细菌性心内膜炎导致大量三尖瓣反流。三尖瓣置换术同时进行了19次右心室心内膜切除术、2次室间隔缺损直接闭合术、2次Wooler二尖瓣成形术和1次心包切除术。手术死亡率为13.5%,二次死亡率为13.5%。16名幸存者中,13人处于纽约心脏协会(NYHA)I级,无需常规药物治疗。他们的心胸比率略有下降。2例患者有永久性房颤,12例有获得性完全性右束支传导阻滞。其中8例患者术后导管检查时心房和右心室压力、Yu氏指数和心脏指数有显著改善。16例患者中有3例生物瓣出现进行性钙化退变。他们是随访超过3年的6例患者中的一部分。再次手术时无死亡病例。尽管这些患者年龄较轻,但由于机械瓣存在与瓣膜卡瓣和血栓形成相关的高得多的死亡率等缺点,所以选择了生物瓣单独三尖瓣置换术。与二尖瓣、主动脉瓣或微主动脉瓣置换术相比,这一系列单独三尖瓣置换术相对较高的手术和二次死亡率与潜在病因病理的严重性有关。

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