Neeha Saara, Kattimani Santosh Rao, Mahanta Anita A, Patil Anuradha G
Department of Pathology, Mahadevappa Rampure Medical College, Kalaburagi, Karnataka, India.
Indian J Pathol Microbiol. 2018 Oct-Dec;61(4):495-499. doi: 10.4103/IJPM.IJPM_461_17.
: Fetal autopsy has been an indispensable tool in evaluating the cause of death. The most common cause for fetal deaths is associated with respiratory disorders accounting for around 60%. This study was undertaken to evaluate the gross and microscopic features of lungs in fetal autopsies and estimate the incidence of deaths attributable to pulmonary causes.
: All fetuses received for autopsy at our institute were included in the study with prior consent. Gross and microscopic findings along with relevant clinical data were recorded.
A total of 426 autopsies were conducted from January 2011 to August 2016. Of those, 184 had abnormal pulmonary findings constituting 43.19%. Aspiration pneumonia was the most common finding with 67 cases (36.4%), followed by atelectasis 54 cases (29.3%), congenital cystic adenomatoid malformation in 13 cases (7.1%), lung hypoplasia 12 cases (6.5%), pulmonary hemorrhage 21 (11.4%), 15 cases (8.15%) of hyaline membrane disease, one case (0.5%) of heterotaxy, and one case of extralobar pulmonary sequestration (0.5%). Congenital malformations of lungs were seen in 27 (14.67%) cases and 38 cases (20.65%) had other associated anomalies.
Pulmonary pathology is the most common finding in fetal deaths with aspiration pneumonitis being the most common avoidable cause. Accurate fetal autopsy along with clinical data are important in evaluating fetal deaths and can help in reduction of unexplained stillbirths.
胎儿尸检一直是评估死亡原因不可或缺的工具。胎儿死亡最常见的原因与呼吸系统疾病相关，约占60%。本研究旨在评估胎儿尸检中肺部的大体和微观特征，并估计肺部原因导致的死亡发生率。
经事先同意，本研究所接收的所有用于尸检的胎儿均纳入本研究。记录大体和微观检查结果以及相关临床数据。
2011年1月至2016年8月共进行了426例尸检。其中，184例有肺部异常发现，占43.19%。吸入性肺炎是最常见的发现，有67例（36.4%），其次是肺不张54例（29.3%），先天性囊性腺瘤样畸形13例（7.1%），肺发育不全12例（6.5%），肺出血21例（11.4%），透明膜病15例（8.15%），异位1例（0.5%），肺叶外隔离症1例（0.5%）。27例（14.67%）有先天性肺部畸形，38例（20.65%）有其他相关异常。
肺部病理是胎儿死亡最常见的发现，吸入性肺炎是最常见的可避免原因。准确的胎儿尸检以及临床数据对于评估胎儿死亡很重要，有助于减少不明原因的死产。
