Lin Yu-Hua, Liao Chun-Hou, Jiang Bing-Jun, Chen Tzu-Hung
Division of Urology, Department of Surgery, Cardinal Tien Hospital, New Taipei, Taiwan.
Department of Urology, National Taiwan University Hospital, Taipei, Taiwan.
Tzu Chi Med J. 2018 Oct-Dec;30(4):250-254. doi: 10.4103/tcmj.tcmj_180_17.
Vascular complications are serious problems after kidney transplantation. An aneurysm or rupture in a graft artery is a rare but potentially devastating complication, which may lead to renal function impairment, graft loss, or even death. In this paper, we present two rare vascular complications in the early postoperative course after renal transplantation from the same deceased donor. In the first case, a 49-year-old woman who had spontaneous graft arterial rupture 13 days after kidney transplantation presented with sudden distension in the right lower abdomen. In the second case, a 56-year-old woman recipient with a graft renal arterial pseudoaneurysm presented with decreased urine output and deteriorating renal function 32 days after transplantation. Immediate surgical repair was performed, and fibrin sealant was applied to strengthen the fragile renal arterial wall. Although the function of both graft kidneys recovered well after surgery, the first graft kidney was removed 2 months later because of repeated fungal and bacterial infections. Aggressive surgical reconstruction may preserve graft kidneys in patients with vascular complications after kidney transplantation, but recovery of the graft condition remains a demanding challenge in renal transplantation.
血管并发症是肾移植术后的严重问题。移植肾动脉的动脉瘤或破裂是一种罕见但可能具有毁灭性的并发症,可能导致肾功能损害、移植肾丧失,甚至死亡。在本文中,我们呈现了来自同一已故供体的肾移植术后早期出现的两例罕见血管并发症。第一例中,一名49岁女性在肾移植术后13天出现移植肾动脉自发性破裂,表现为右下腹突然膨隆。第二例中,一名56岁女性受者在移植术后32天出现移植肾动脉假性动脉瘤,表现为尿量减少和肾功能恶化。立即进行了手术修复,并应用纤维蛋白密封剂加固脆弱的肾动脉壁。尽管两个移植肾在术后功能恢复良好,但由于反复发生真菌和细菌感染,第一个移植肾在2个月后被切除。积极的手术重建可能使肾移植术后出现血管并发症的患者保留移植肾,但移植肾状况的恢复在肾移植中仍然是一项艰巨的挑战。