脑损伤作为单侧脑瘫婴儿手部功能治疗结果的预测指标
Brain Lesions as a Predictor of Therapeutic Outcomes of Hand Function in Infants With Unilateral Cerebral Palsy.
作者信息
Chamudot Rena, Parush Shula, Rigbi Amihai, Gross-Tsur Varda
机构信息
1 School of Occupational Therapy, Faculty of Medicine, Hebrew University of Jerusalem, Israel.
2 Research Authority and Faculty of Education, Beit Berl Academic College, Kfar-Sava, Israel.
出版信息
J Child Neurol. 2018 Dec;33(14):918-924. doi: 10.1177/0883073818801632. Epub 2018 Oct 11.
AIM
The present study aimed to investigate whether the response variability of infants to modified constraint-induced movement therapy and bimanual therapy are associated with different types of brain lesions.
METHOD
Infants with unilateral cerebral palsy (N = 22) ages 8-15 months (mean = 10.95, standard deviation = 2.15 months) were grouped according to having either a periventricular brain lesion or a middle cerebral artery infarct lesion. Improvement in hand function was analyzed based on the mini-Assistive Hand Assessment results.
RESULTS
Infants with periventricular brain lesion displayed greater positive response to upper limb treatment compared to those with middle cerebral artery infarct ( P = .02). A significant difference in improvement according to type of treatment was found in the middle cerebral artery infarct group but not in the periventricular brain lesion.
CONCLUSION
The present study showed an association between the type of brain lesion and the efficacy of upper limb treatment in infants. Infants with periventricular brain lesions displayed greater positive responses than those with middle cerebral artery infarct.
目的
本研究旨在探讨婴儿对改良的强制性运动疗法和双手疗法的反应变异性是否与不同类型的脑损伤相关。
方法
将22名年龄在8至15个月（平均 = 10.95，标准差 = 2.15个月）的单侧脑瘫婴儿，根据是否患有脑室周围脑损伤或大脑中动脉梗死性损伤进行分组。基于小型辅助手评估结果分析手功能的改善情况。
结果
与患有大脑中动脉梗死的婴儿相比，患有脑室周围脑损伤的婴儿对上肢治疗表现出更大的积极反应（P = .02）。在大脑中动脉梗死组中，根据治疗类型的改善存在显著差异，但在脑室周围脑损伤组中未发现。
结论
本研究表明脑损伤类型与婴儿上肢治疗效果之间存在关联。患有脑室周围脑损伤的婴儿比患有大脑中动脉梗死的婴儿表现出更大的积极反应。
Zotero 插件