Alford B R, Cohn A M, Igarashi M
Ann Otol Rhinol Laryngol. 1977 Sep-Oct;86(5 Pt 1):683-8. doi: 10.1177/000348947708600526.
At the present time, neither the etiologic factors nor the pathophysiologic mechanisms that lead to the development of endolymphatic hydrops or Ménière's disease are known; however, the anatomic-pathologic alterations in the labyrinth that are produced by the disease are well-documented. Undoubtedly, what is not known is responsible for the controversial status and questionable benefit that surgical decompression and drainage procedures have upon the endolymphatic system.
目前,导致内淋巴积水或梅尼埃病发生的病因及病理生理机制均尚不明确;然而,该疾病所引起的内耳迷路的解剖病理改变已有充分记录。毫无疑问,正是由于尚不明确的因素,导致了手术减压和引流对内淋巴系统的治疗处于争议状态且疗效存疑。