Lee Kau-Han, Kuo Hann-Chorng
Division of Urology, Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan.
Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan.
Urology. 2019 Jan;123:235-241. doi: 10.1016/j.urology.2018.09.030. Epub 2018 Oct 9.
The aim of this study is to investigate the treatment outcome in men with detrusor underactivity (DU) and voiding dysfunction who underwent transurethral resection or incision of the prostate (TURP or TUIP). DU usually affects decision making whether bladder outlet surgery is necessary.
A total of 60 men with urodynamic DU and voiding dysfunction who underwent TURP or TUIP from 1998 to 2015 were retrospectively analyzed for their treatment outcome after follow-up for more than 1 year. DU was defined as urodynamic evidence of low detrusor pressure (<40 cm HO), low flow rate (<10 mL/s), a postvoid residual urine volume >300 mL, and a voiding efficiency (VE) of <33%. Satisfactory outcome was defined as improved quality of life and having a VE of >50% after treatment. Predictive factor for a successful outcome was also analyzed.
At a mean follow-up of 31 months, 49 (81.7%) patients had achieved a satisfactory treatment outcome. Among the patients who received TURP and TUIP, 38/44 (86.4%) and 11/16 (68.8%) had satisfactory outcome, respectively. The satisfactory group had significantly higher detrusor pressure and greater bladder compliance at baseline than the unsatisfactory group. There was significant improvement in the urodynamic parameters after treatment in the satisfactory group. Among the patients with satisfactory outcome, 34 (69.4%) patients had recovery of detrusor function within 3 months.
Active surgical treatment such as TURP or TUIP results in recovery of VE and detrusor function within 3 months after treatment in the majority of patients with DU.
本研究旨在调查接受经尿道前列腺切除术或前列腺切开术(TURP或TUIP)的逼尿肌活动低下(DU)和排尿功能障碍男性患者的治疗结果。DU通常会影响是否需要进行膀胱出口手术的决策。
回顾性分析了1998年至2015年间共60例接受TURP或TUIP的尿动力学DU和排尿功能障碍男性患者,随访时间超过1年,分析其治疗结果。DU定义为尿动力学显示逼尿肌压力低(<40 cmH₂O)、尿流率低(<10 mL/s)、排尿后残余尿量>300 mL以及排尿效率(VE)<33%。满意的结果定义为生活质量改善且治疗后VE>50%。还分析了成功结果的预测因素。
平均随访31个月时,49例(81.7%)患者获得了满意的治疗结果。在接受TURP和TUIP的患者中,分别有38/44(86.4%)和11/16(68.8%)获得了满意的结果。满意组在基线时的逼尿肌压力和膀胱顺应性明显高于不满意组。满意组治疗后尿动力学参数有显著改善。在获得满意结果的患者中,34例(69.4%)患者在3个月内逼尿肌功能恢复。
对于大多数DU患者,积极手术治疗如TURP或TUIP可使治疗后3个月内VE和逼尿肌功能恢复。