Damm Robert, El-Sanosy Shahen, Omari Jazan, Damm Romy, Hass Peter, Pech Maciej, Powerski Maciej
Department of Radiology and Nuclear Medicine, University of Magdeburg, Germany.
Department of Radiotherapy, University of Magdeburg, Germany.
Rofo. 2019 Jan;191(1):48-53. doi: 10.1055/a-0636-4055. Epub 2018 Oct 11.
To evaluate the safety and feasibility of sonographically-assisted catheter placement in interstitial high-dose-rate brachytherapy of abdominal malignancies.
In an initial cohort of 12 patients and 16 abdominal tumors (colorectal liver metastases n = 9; renal cell cancer n = 3; hepatocellular carcinoma n = 2; cholangiocellular carcinoma n = 2), initial puncture and catheter placement for CT-guided brachytherapy were performed under sonographic assistance when possible. The interventional procedure was prospectively recorded and in-patient data were collected. All data underwent descriptive statistics and comparative analysis by the Mann-Whitney test.
In 12 out of 16 lesions (diameter 1.5 - 12.9 cm), initial puncture was successfully achieved under ultrasound guidance without utilization of CT fluoroscopy, yielding a significantly shorter mean total fluoroscopy time (14.5 vs. 105.5 s; p = 0.006). In 8 lesions visibility was rated better in ultrasound than in CT fluoroscopy (p = 0.2). No major or minor complications occurred within 30 days after treatment.
Ultrasound-assisted catheter placement during interstitial CT-guided brachytherapy of abdominal tumors could improve catheter positioning and reduce radiation exposure for medical staff.
Ultrasound-assisted catheter placement in CT-guided brachytherapy is safe and feasible. Ultrasound puncture may improve catheter positioning. Reduced CT fluoroscopy time can significantly help to minimize radiation exposure for medical staff.
· Damm R, El-Sanosy S, Omari J et al. Ultrasound-assisted catheter placement in CT-guided HDR brachytherapy for the local ablation of abdominal malignancies: Initial experience. Fortschr Röntgenstr 2019; 191: 48 - 53.
评估超声辅助下导管置入在腹部恶性肿瘤组织间高剂量率近距离放射治疗中的安全性和可行性。
在最初的12例患者和16个腹部肿瘤(结直肠癌肝转移9例;肾细胞癌3例;肝细胞癌2例;胆管细胞癌2例)队列中,尽可能在超声辅助下进行CT引导近距离放射治疗的初始穿刺和导管置入。前瞻性记录介入过程并收集住院患者数据。所有数据进行描述性统计,并通过Mann-Whitney检验进行比较分析。
在16个病灶中的12个(直径1.5 - 12.9 cm),在超声引导下成功完成初始穿刺,无需使用CT透视,平均总透视时间显著缩短(14.5秒对105.5秒;p = 0.006)。在8个病灶中,超声下的可视性被评为优于CT透视(p = 0.2)。治疗后30天内未发生任何严重或轻微并发症。
在腹部肿瘤的CT引导组织间近距离放射治疗中,超声辅助导管置入可改善导管定位,并减少医护人员的辐射暴露。
超声辅助CT引导下的近距离放射治疗中导管置入安全可行。超声穿刺可改善导管定位。减少CT透视时间可显著帮助医护人员减少辐射暴露。
· Damm R, El-Sanosy S, Omari J等。超声辅助导管置入在CT引导的高剂量率近距离放射治疗中用于腹部恶性肿瘤局部消融:初步经验。Fortschr Röntgenstr 2019; 191: 48 - 53。