Naruke Yuki, Horie Hiroshi, Nagai Yuichiro, Ando Ryo
Clin Neuropathol. 2019 Jan/Feb;38(1):33-37. doi: 10.5414/NP301117.
Filar lipomas are a subtype of spinal lipomas wherein adipose tissue accumulation is restricted to the filum terminale. Embryologically, filar lipomas are considered to occur because of the failure of secondary neurulation, although the precise mechanism is not yet completely understood. Involvement of ectopic mesodermal, ectodermal, and endodermal tissues in spinal lipomas has been occasionally reported, and the origin of these ectopic tissues has been supposed to be migration of pluripotent tissues, which exist during secondary neurulation. We report an infantile case of capillary hemangioma involved in filar lipoma. To our knowledge, this is the first report of a case of intradural extramedullary capillary hemangioma at the filum terminale. We suspected that the filar lesion arose during the late phase of secondary neurulation based on the clinical, anatomical, and histological characteristics. .
终丝脂肪瘤是脊髓脂肪瘤的一种亚型，其中脂肪组织的积聚局限于终丝。从胚胎学角度来看，尽管确切机制尚未完全明确，但终丝脂肪瘤被认为是由于继发性神经管形成失败所致。脊髓脂肪瘤偶尔会累及异位的中胚层、外胚层和内胚层组织，这些异位组织的起源被认为是继发性神经管形成过程中存在的多能组织的迁移。我们报告了一例终丝脂肪瘤合并毛细血管瘤的婴儿病例。据我们所知，这是首例关于终丝硬膜内髓外毛细血管瘤病例的报告。基于临床、解剖和组织学特征，我们怀疑该终丝病变发生于继发性神经管形成的晚期。
