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An Intravenous Fish Oil-Based Lipid Emulsion Successfully Treats Intractable Pruritus and Cholestasis in a Patient with Microvillous Inclusion Disease.

作者信息

Anez-Bustillos Lorenzo, Dao Duy T, Potemkin Alexis K, Perez-Atayde Antonio R, Raphael Bram P, Carey Alexandra N, Kamin Daniel S, Thiagarajah Jay R, Crowley McGreggor, Gura Kathleen M, Puder Mark

机构信息

Vascular Biology Program and the Department of Surgery, Boston Children's Hospital, Boston, MA.

Department of Pathology, Boston Children's Hospital, Boston, MA.

出版信息

Hepatology. 2019 Mar;69(3):1353-1356. doi: 10.1002/hep.30311. Epub 2019 Feb 9.

DOI:10.1002/hep.30311
PMID:30311684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6507398/
Abstract
摘要

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Inhalation of nebulized omega-3 fatty acids mitigate LPS-induced acute lung inflammation in rats: Implications for treatment of COPD and COVID-19.雾化 ω-3 脂肪酸吸入减轻脂多糖诱导的大鼠急性肺炎症：对 COPD 和 COVID-19 治疗的启示。
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本文引用的文献

1
Defects in myosin VB are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis.肌球蛋白VB缺陷与一系列先前未被诊断出的低γ-谷氨酰转移酶胆汁淤积症有关。
Hepatology. 2017 May;65(5):1655-1669. doi: 10.1002/hep.29020. Epub 2017 Mar 23.
2
MYO5B mutations cause cholestasis with normal serum gamma-glutamyl transferase activity in children without microvillous inclusion disease.MYO5B 突变导致儿童胆汁淤积症伴正常血清 γ-谷氨酰转移酶活性，而无微绒毛包涵体病。
Hepatology. 2017 Jan;65(1):164-173. doi: 10.1002/hep.28779. Epub 2016 Oct 5.
3
MYO5B and bile salt export pump contribute to cholestatic liver disorder in microvillous inclusion disease.
基于药理和肠外营养的微绒毛包涵体病干预措施
J Clin Med. 2020 Dec 23;10(1):22. doi: 10.3390/jcm10010022.
4
Unequal Effects of Myosin 5B Mutations in Liver and Intestine Determine the Clinical Presentation of Low-Gamma-Glutamyltransferase Cholestasis.肌球蛋白5B突变在肝脏和肠道中的不同作用决定了低γ-谷氨酰转移酶胆汁淤积症的临床表现。
Hepatology. 2020 Oct;72(4):1461-1468. doi: 10.1002/hep.31430.
5
A Molecular Mechanism Underlying Genotype-Specific Intrahepatic Cholestasis Resulting From MYO5B Mutations.一种由 MYO5B 突变引起的基因型特异性肝内胆汁淤积的分子机制。
Hepatology. 2020 Jul;72(1):213-229. doi: 10.1002/hep.31002. Epub 2020 Apr 23.
MYO5B 和胆汁盐输出泵导致微绒毛包涵体病中的胆汁淤积性肝病。
Hepatology. 2014 Jul;60(1):301-10. doi: 10.1002/hep.26974. Epub 2014 May 27.
4
Dietary supplementation with ethyl ester concentrates of fish oil (n-3) and borage oil (n-6) polyunsaturated fatty acids induces epidermal generation of local putative anti-inflammatory metabolites.膳食补充鱼油（n-3）和琉璃苣油（n-6）多不饱和脂肪酸的乙酯浓缩物可诱导表皮产生局部假定的抗炎代谢产物。
J Invest Dermatol. 1991 Jan;96(1):98-103. doi: 10.1111/1523-1747.ep12515911.