Univ. Lille, CHU Lille, INSERM, U1171 - Degenerative & Vascular Cognitive Disorders, F-59000 Lille, France; Lille Centre of Excellence for Neurodegenerative Diseases (LiCEND), F-59000 Lille, France.
Univ. Lille, CHU Lille, INSERM, U1171 - Degenerative & Vascular Cognitive Disorders, F-59000 Lille, France; Lille Centre of Excellence for Neurodegenerative Diseases (LiCEND), F-59000 Lille, France.
Neuroscience. 2018 Nov 21;393:12-23. doi: 10.1016/j.neuroscience.2018.09.046. Epub 2018 Oct 10.
Gait initiation can vary as a function of the available and engaged attentional resources. Conflict resolution can disrupt movement preparation and lead to "errors" in motor programming. These "errors" are physiologically useful by enabling us to adapt our motor behavior to situations with conflicting information. The objective of the present study was to analyze the patterns of cortical activation associated with motor programming errors and the corresponding error corrections. Incongruent flankers around a target arrow were used to trigger errors in anticipatory postural adjustments (APAs) prior to gait initiation; i.e. perturbed motor programming but normal execution. Thirty healthy adults performed a gait initiation task. The event-related potentials (ERPs) and event-related desynchronization (ERD) after target presentation were analyzed according to the presence or absence of an APA error. The ERP was similar in both conditions, except that the Ne and P300 peak latencies were longer for APA errors. Motor programming errors during gait initiation were characterized by longer, less intense low-beta-band ERD over the sensorimotor cortex and alpha ERS followed by stronger alpha ERD during errors. APA errors were associated with a specific alpha/beta oscillation profile over the sensorimotor cortex; these beta oscillations might be sensitive markers of non-conscious motor error and correction monitoring.
步态启动可以根据可用的和参与的注意力资源而有所不同。冲突解决会破坏运动准备，并导致运动编程中的“错误”。这些“错误”在生理上是有用的，因为它们使我们能够根据有冲突信息的情况调整我们的运动行为。本研究的目的是分析与运动编程错误和相应错误纠正相关的皮层激活模式。在步态启动之前，目标箭头周围的不一致侧标会引发预期姿势调整（APAs）中的错误，即干扰运动编程但正常执行。30 名健康成年人执行了步态启动任务。根据是否存在 APA 错误，分析了目标呈现后的事件相关电位（ERPs）和事件相关去同步（ERD）。两种情况下的 ERP 相似，除了 Ne 和 P300 峰潜伏期在 APA 错误时更长。步态启动过程中的运动编程错误表现为感觉运动皮层上持续时间更长、强度更低的低频波段 ERD 和错误后更强的 alpha ERD。APA 错误与感觉运动皮层上特定的 alpha/beta 振荡模式相关；这些 beta 振荡可能是无意识运动错误和校正监测的敏感标志物。
