Hu Bolin, Zhou Yibiao, Lu Xiaoqing, Xiong Qianqian, Liu Qing, Qi Xueliang, Ding Weijiang
Department of Neurology, The Second Affiliated Hospital of Nanchang University.
Department of Orthopaedics, The First Affiliated Hospital of Nanchang University, Nanchang Shi, Jiangxi Sheng, China.
Medicine (Baltimore). 2018 Oct;97(41):e12469. doi: 10.1097/MD.0000000000012469.
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a disorder characterized by a symmetrical, sensorimotor involvement and slowly progressive onset peripheral neuropathy. Peripheral neuropathies have been reported in some central demyelination patients. However, the central nervous system focus in the CIDP patient can mimic neuromyelitis optica have not been recognized by most of us.
The numbness and weakness of limbs about eight weeks.
Chronic inflammatory demyelinating polyradiculoneuropathy.
Immunotherapy with intravenous immunoglobulins was applied to this patient.
After 1 year follow-up, the results showed there was still slight numbness of all limbs, and he could walk slowly without help. Gastrocnemius muscle atrophy did not aggravate.
So It is suggest that CIDP can combine with central lesions mimicking neuromyelitis optica. We should take the diagnosis of CIDP into consideration when we find focus in central nervous system.
慢性炎症性脱髓鞘性多发性神经根神经病(CIDP)是一种以对称性、感觉运动受累及缓慢进展性起病的周围神经病为特征的疾病。在一些中枢性脱髓鞘患者中曾有周围神经病的报道。然而,大多数人尚未认识到CIDP患者的中枢神经系统病变可酷似视神经脊髓炎。
四肢麻木、无力约8周。
慢性炎症性脱髓鞘性多发性神经根神经病。
对该患者应用静脉注射免疫球蛋白进行免疫治疗。
经过1年随访,结果显示四肢仍有轻微麻木,他可在无人帮助下缓慢行走。腓肠肌萎缩未加重。
提示CIDP可合并酷似视神经脊髓炎的中枢性病变。当发现中枢神经系统病变时应考虑CIDP的诊断。