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院前环境下,基础生命支持提供者将ST段抬高型心肌梗死患者转运至经皮冠状动脉介入治疗机构的安全性。

The Safety of Bypass to Percutaneous Coronary Intervention Facility by Basic Life Support Providers in Patients with ST-Elevation Myocardial Infarction in Prehospital Setting.

作者信息

Froats Mark, Reed Andrew, Dionne Richard, Maloney Justin, Duncan Susan, Burns Rob, Sinclair Julie, Austin Michael

机构信息

Department of Emergency Medicine, Queen's University, Kingston, Ontario, Canada; Regional Paramedic Program for Eastern Ontario, Ottawa, Ontario, Canada; Department of Emergency Medicine, University of Ottawa, Ontario, Canada.

Department of Emergency Medicine, Queen's University, Kingston, Ontario, Canada; Regional Paramedic Program for Eastern Ontario, Ottawa, Ontario, Canada.

出版信息

J Emerg Med. 2018 Dec;55(6):792-798. doi: 10.1016/j.jemermed.2018.09.006. Epub 2018 Oct 9.

DOI:10.1016/j.jemermed.2018.09.006
PMID:30314928
Abstract

BACKGROUND

Most patients transferred from a non-percutaneous coronary intervention (PCI) facility for primary PCI do not meet target reperfusion times. Direct transportation of patients with ST-elevation myocardial infarction (STEMI) from the scene by advanced life support (ALS) paramedics has been shown to improve reperfusion times and outcomes.

OBJECTIVE

The aim of this study was to determine whether it is safe to bypass the closest hospital and transport by basic life support (BLS) provider to a PCI facility.

METHODS

This was a health records review of consecutive patients transported to a regional PCI center under an STEMI bypass protocol. Under the PCI bypass protocol, patients were eligible if they presented with symptoms of chest pain, a 12-lead electrocardiogram meeting STEMI criteria, and if transported to the regional PCI center within 60 min. The occurrence of predefined adverse events during transport was determined, which included bradycardia < 50 beats/min, tachycardia > 140 beats/min, hypotension, cardiac arrest, and death.

RESULTS

There were 46 cases of STEMI bypass between February 2005 and February 2013. Mean transport time was 29.9 min (range 20-62 min). Mean contact-to-balloon time was 95.2 min (range 68-159 min). Twenty-five adverse events occurred in 20 patients during transport. In 16 of the 20 patients, the adverse events were transiently abnormal vital sign requiring no intervention. In 3 of the patients, the adverse event was clinically significant and it is believed that the patient would have benefitted from advanced cardiac life support care not within the scope of practice of the BLS providers.

CONCLUSIONS

In our region, STEMI patients can be diagnosed accurately and transported safely on bypass to a PCI center for primary PCI while respecting target reperfusion times.

摘要

背景

大多数从非经皮冠状动脉介入治疗(PCI)机构转运至行直接PCI的患者未达到目标再灌注时间。高级生命支持(ALS)医护人员将ST段抬高型心肌梗死(STEMI)患者从现场直接转运已被证明可改善再灌注时间和治疗结果。

目的

本研究旨在确定绕过距离最近的医院,由基础生命支持(BLS)人员转运至PCI机构是否安全。

方法

这是一项对按照STEMI转运方案转运至区域PCI中心的连续患者的健康记录回顾。根据PCI转运方案,患者若出现胸痛症状、12导联心电图符合STEMI标准且在60分钟内转运至区域PCI中心,则符合入选条件。确定转运期间预先定义的不良事件的发生情况,包括心率<50次/分钟的心动过缓、心率>140次/分钟的心动过速、低血压、心脏骤停和死亡。

结果

2005年2月至2013年2月期间有46例STEMI转运病例。平均转运时间为29.9分钟(范围20 - 62分钟)。平均接触球囊时间为95.2分钟(范围68 - 159分钟)。20例患者在转运期间发生了25起不良事件。在这20例患者中的16例中,不良事件为生命体征短暂异常,无需干预。在3例患者中,不良事件具有临床意义,据信患者本可从超出BLS人员执业范围的高级心脏生命支持护理中获益。

结论

在我们地区,STEMI患者可以在尊重目标再灌注时间的情况下,被准确诊断并安全地绕过医院转运至PCI中心进行直接PCI。

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