Spalla M, Kuo T H, Wiener J
Muscle Nerve. 1987 Jan;10(1):54-9. doi: 10.1002/mus.880100111.
A high calcium-requiring protease was purified from the hearts of myopathic hamsters. The biochemical properties of the enzyme were studied with [3H]acetylcasein as substrate. Comparison of the enzyme from hamster and rat hearts indicated no species specificity. Increased levels of the enzyme were associated with the development of cardiac lesions in myopathic hamsters.
从患肌病仓鼠的心脏中纯化出一种高钙需求蛋白酶。以[3H]乙酰酪蛋白为底物研究了该酶的生化特性。对仓鼠和大鼠心脏中的酶进行比较,结果表明没有种属特异性。该酶水平的升高与患肌病仓鼠心脏病变的发展有关。