Department of Neurosurgery, Winterthur Cantonal Hospital, Brauerstrasse 15, 8401, Winterthur, Switzerland.
Department of Pathology, Winterthur Cantonal Hospital, Brauerstrasse 15, 8401, Winterthur, Switzerland.
Acta Neurochir (Wien). 2018 Dec;160(12):2393-2396. doi: 10.1007/s00701-018-3700-z. Epub 2018 Oct 13.
Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms commonly involving visceral or parietal pleura. We present the first report of tumor-to-tumor metastasis involving a pulmonary adenocarcinoma donor and an intradural SFT recipient. The patient presented with a 1 year history of diffuse back pain. A spinal intradural contrast-enhancing mass at the T9/10 level and a tumor of the lung were diagnosed radiologically. Bronchoscopic biopsy confirmed pulmonary adenocarcinoma in the right upper lung lobe. Due to deteriorating neurological status with conus medullaris syndrome, we performed a neurosurgical excision of the lesion. Histological analysis of the tumor revealed tumor-to-tumor metastasis of the adenocarcinoma to the SFT.
孤立性纤维瘤（SFT）是一种罕见的间叶性肿瘤，通常累及内脏或壁层胸膜。我们首次报道了涉及肺腺癌供体和硬脊膜内 SFT 受体的肿瘤对肿瘤转移。患者表现为弥漫性背痛 1 年。影像学诊断为 T9/10 水平硬脊膜内对比增强肿块和肺部肿瘤。支气管镜活检证实右上肺叶腺癌。由于圆锥综合征的神经状态恶化，我们对病变进行了神经外科切除。肿瘤的组织学分析显示腺癌对 SFT 的肿瘤对肿瘤转移。
