Martin T, Mantey K, Boissier R, Albert P, Grisoni V, Lechevallier E, Barriol D, Gravis G, Pignot G, Rossi D, Lorca J, Rattier C, Eghazarian C, Daou N, Davin J L, Clément C, Akiki A, Pascal L, Karsenty G
Service d'urologie et de transplantation rénale, hôpital de la Conception, 147, boulevard Baille, 13005 Marseille, France; Service d'urologie, hôpital Edmond Garcin, 13400 Aubagne, France.
Observatoire régional d'épidémiologie pour la région PACA, 13005 Marseille, France.
Prog Urol. 2018 Dec;28(16):935-941. doi: 10.1016/j.purol.2018.09.004. Epub 2018 Oct 10.
The REVELA13 observatory is a unique epidemiological tool listing the new cases of kidney tumors, bladder tumors and acute leukaemias in the Bouches-du-Rhône county (France). Aim was to exploit for the first time data from this observatory regarding new cases of bladder tumors≥T1 in women from 2012 to 2014.
This epidemiological study was observational and descriptive. Fifteen non-nominative variables from the REVELA13 database were analyzed in order to describe the clinical and pathological characteristics of the incident cases as well as their spatial and temporal distribution. The incidence rates expressed in new cases per year per 100000 inhabitants were standardized on the world age, calculated with 95 % confidence intervals and compared to national estimates for the same period.
Incident bladder tumor cases were recorded in 291 women, corresponding to a standardized incidence on the world age of 3.85 [3.32-4.37] new cases per year per 100,000 population, 54 % higher than the national estimates of 2012 and 2015. Median age of diagnostic was 75.9 years. Sex ratio was 19.41 % (W/M). Tumors were predominantly non-muscle-invasive (52 %), high grade (69 %) and without associated carcinoma in situ (Cis) (49 %). The two most affected territories were Marseille and Aubagne-La Ciotat.
The REVELA13 observatory has improved our epidemiological knowledge on female bladder tumors in Bouches-du-Rhône county and highlighted a local over incidence.
REVELA13监测站是一种独特的流行病学工具，用于记录法国罗讷河口省肾肿瘤、膀胱肿瘤和急性白血病的新发病例。目的是首次利用该监测站2012年至2014年期间女性膀胱肿瘤≥T1新发病例的数据。
本流行病学研究为观察性和描述性研究。分析了REVELA13数据库中的15个非命名变量，以描述发病病例的临床和病理特征及其时空分布。发病率以每10万居民每年的新发病例数表示，并根据世界年龄进行标准化，计算95%置信区间，并与同期的全国估计数进行比较。
记录了291例女性膀胱肿瘤发病病例，世界年龄标准化发病率为每10万人口每年3.85例[3.32-4.37]，比2012年和2015年的全国估计数高54%。诊断时的中位年龄为75.9岁。性别比为19.41%（女性/男性）。肿瘤主要为非肌层浸润性（52%）、高级别（69%）且无原位癌（Cis）（49%）。受影响最严重的两个地区是马赛和奥巴涅-拉乔塔。
REVELA13监测站提高了我们对罗讷河口省女性膀胱肿瘤的流行病学认识，并突出了当地发病率过高的情况。
3级。
