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ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer.

作者信息

Bakkenist Christopher J, Lee James J, Schmitz John C

机构信息

Department of Radiation Oncology, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, Pittsburgh, PA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, Pittsburgh, PA.

Department of Medicine, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, Pittsburgh, PA.

出版信息

Clin Colorectal Cancer. 2018 Dec;17(4):255-257. doi: 10.1016/j.clcc.2018.09.001. Epub 2018 Sep 13.

Abstract
摘要

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本文引用的文献

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Ataxia Telangiectasia Mutated Protein Loss and Benefit From Oxaliplatin-based Chemotherapy in Colorectal Cancer.
Clin Colorectal Cancer. 2018 Dec;17(4):280-284. doi: 10.1016/j.clcc.2018.05.011. Epub 2018 Jun 8.
2
The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy.
Oncotarget. 2017 Dec 5;8(67):110904-110913. doi: 10.18632/oncotarget.22920. eCollection 2017 Dec 19.
3
ATM Mutations in Cancer: Therapeutic Implications.
Mol Cancer Ther. 2016 Aug;15(8):1781-91. doi: 10.1158/1535-7163.MCT-15-0945. Epub 2016 Jul 13.
4
ATM protein is deficient in over 40% of lung adenocarcinomas.
Oncotarget. 2016 Sep 6;7(36):57714-57725. doi: 10.18632/oncotarget.9757.
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Brd4 shields chromatin from ATM kinase signaling storms.
Sci Signal. 2013 Sep 17;6(293):pe30. doi: 10.1126/scisignal.2004622.
9
Radiation therapy induces the DNA damage response in peripheral blood.
Oncotarget. 2013 Aug;4(8):1143-8. doi: 10.18632/oncotarget.1084.

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