Sharma O P, Anders A
Sarcoidosis. 1985 Sep;2(2):96-106.
The common and not so common neurologic lesions due to sarcoidosis include cranial nerve palsies, meningitis, hypothalamic and pituitary lesions, basilar meningitis, polyneuropathy, space occupying lesions and spinal cord involvement. The diagnosis of neurosarcoidosis requires a compatible clinical or radiologic picture of sarcoidosis and histological confirmation of noncaseating granulomas. Serum ACE, Gallium-67 lung scan and bronchoalveolar lavage are of help in supporting the diagnosis and establishing activity of the disease. A CT scan with enhancement is the diagnostic procedure of choice. Corticosteroids are the cornerstone of therapy.
结节病所致的常见及不那么常见的神经病变包括颅神经麻痹、脑膜炎、下丘脑和垂体病变、基底脑膜炎、多发性神经病、占位性病变及脊髓受累。神经结节病的诊断需要有符合结节病的临床或影像学表现以及非干酪样肉芽肿的组织学证实。血清血管紧张素转换酶(ACE)、镓-67肺扫描及支气管肺泡灌洗有助于支持诊断并确定疾病的活动度。增强CT扫描是首选的诊断方法。皮质类固醇是治疗的基石。