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胆脂瘤手术中术中内镜二次探查的临床及成本效益

Clinical and cost utility of an intraoperative endoscopic second look in cholesteatoma surgery.

作者信息

Bennett Marc, Wanna George, Francis David, Murfee Jack, O'Connell Brendan, Haynes David

机构信息

Department of Otolaryngology, Vanderbilt University Medical Center, Nashville, Tennessee.

Department of Otolaryngology, Mt. Sinai Medical Center, New York, New York.

出版信息

Laryngoscope. 2018 Dec;128(12):2867-2871. doi: 10.1002/lary.27258. Epub 2018 Oct 16.

Abstract

OBJECTIVE/HYPOTHESIS: This study aimed to determine the clinical and cost-effectiveness of endoscopes during cholesteatoma surgery. More specifically, this study hypothesized that endoscope use would reduce cholesteatoma recurrence rates and cost.

STUDY DESIGN

Case series involving the prospective enrollment of 110 consecutive cholesteatoma patients over a 2-year period.

METHODS

Patients underwent cholesteatoma surgery with microscopy. During dissection, the location of the cholesteatoma was assessed. At the end of dissection and before reconstruction, the same subunits were visualized with straight and angled endoscopes for residual cholesteatoma. Hearing was analyzed before surgery and at the last possible examination. Costs were analyzed using Medicare reimbursement rates from the Centers for Medicare and Medicaid Services.

RESULTS

Intraoperative endoscopic surveillance was able to detect residual cholesteatoma in 18 patients. With a 0° endoscope, residual cholesteatoma was noted in the epitympanum (two patients), sinus tympani (one patient), and the supratubal air cells (one patient). With a 45° endoscope, residual cholesteatoma was noted in the epitympanum (three patients), sinus tympani (nine patients), the supratubal air cells (two patients), and the mesotympanum (two patients). From a cost analysis, endoscopic surveillance ($6110.36 per patient) are less expensive than second look surgeries ($11,829.83 per patient), observation ($7097.20 per patient), and observation with annual magnetic resonance imaging studies ($9891.95 per patient). The patients hearing improved after surgery, consistent with previous studies. No complications were noted from the use of endoscopes.

CONCLUSIONS

Intraoperative endoscopic surveillance reduced recurrence in our series of 110 patients. Endoscopes are particularly useful in evaluating the epitympanum, mesotympanum, sinus tympani, and supratubal air cells. Moreover, endoscopic surveillance is cost-effective.

LEVEL OF EVIDENCE

4 Laryngoscope, 128:2867-2871, 2018.

摘要

目的/假设:本研究旨在确定胆脂瘤手术中使用内窥镜的临床效果和成本效益。更具体地说,本研究假设使用内窥镜可降低胆脂瘤复发率并降低成本。

研究设计

病例系列研究,在2年期间前瞻性纳入了110例连续性胆脂瘤患者。

方法

患者接受显微镜下胆脂瘤手术。在解剖过程中,评估胆脂瘤的位置。在解剖结束后和重建前,使用直管和弯管内窥镜观察相同的亚单位,以检查残留胆脂瘤。在手术前和最后一次可行检查时分析听力。使用医疗保险和医疗补助服务中心的医疗保险报销率分析成本。

结果

术中内窥镜监测能够在18例患者中检测到残留胆脂瘤。使用0°内窥镜时,在上鼓室(2例患者)、鼓窦(1例患者)和管上气房(1例患者)发现残留胆脂瘤。使用45°内窥镜时,在上鼓室(3例患者)、鼓窦(9例患者)、管上气房(2例患者)和中鼓室(2例患者)发现残留胆脂瘤。从成本分析来看,内窥镜监测(每位患者6110.36美元)比二次探查手术(每位患者11,829.83美元)、观察(每位患者7097.20美元)以及每年进行磁共振成像检查的观察(每位患者9891.95美元)成本更低。患者术后听力有所改善,与先前研究一致。使用内窥镜未发现并发症。

结论

在我们的110例患者系列中,术中内窥镜监测降低了复发率。内窥镜在评估上鼓室、中鼓室、鼓窦和管上气房方面特别有用。此外,内窥镜监测具有成本效益。

证据级别

4 喉镜,128:2867 - 2871,2018年

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