Mehlisch D R, Taylor T D, Leibold D G, Hiatt R, Waite D E, Waite P D, Laskin D M, Smith S T, Koretz M M
J Oral Maxillofac Surg. 1987 May;45(5):408-13. doi: 10.1016/0278-2391(87)90008-5.
A multicenter study was undertaken to evaluate a new alveolar ridge augmentation material composed of purified fibrillar collagen and particulate hydroxylapatite (PFC/HA). In a study of 77 patients and 99 reconstructed ridges, this material provided superior handling properties over HA alone as evidenced by its ease of surgical placement and manipulation, and the rarity of particle migration or displacement. Moreover, the rapid development of ridge firmness and stability allowed for the loading of dentures within three to six weeks. Prosthodontist evaluations and surveys of patient satisfaction showed great satisfaction with denture fit, comfort, esthetics, speech, and ability to masticate.
开展了一项多中心研究，以评估一种由纯化的纤维状胶原蛋白和颗粒状羟基磷灰石（PFC/HA）组成的新型牙槽嵴增高材料。在一项针对77名患者和99处重建牙槽嵴的研究中，这种材料显示出比单独使用HA更好的操作性能，其易于手术植入和操作，且颗粒迁移或移位的情况罕见。此外，牙槽嵴的硬度和稳定性迅速发展，使得在三到六周内即可佩戴假牙。口腔修复医生的评估和患者满意度调查显示，患者对假牙的贴合度、舒适度、美观度、语音以及咀嚼能力非常满意。
