Yamamoto Nobuharu, Morikawa Takamichi, Yakushiji Takashi, Shibahara Takahiko
Department of Oral and Maxillofacial Surgery, Tokyo Dental College.
Department of Dental and Oral Surgery, National Hospital Organization Takasaki General Medical Center.
Bull Tokyo Dent Coll. 2018 Nov 30;59(4):299-311. doi: 10.2209/tdcpublication.2017-0025. Epub 2018 Oct 18.
An iliac block graft is the most commonly used biomaterial for reconstruction following resection of the mandible. Its use has some disadvantages, however, including limitations on the amount of bone that may be harvested, and the subsequent increase in burden on the iliac bone. Therefore, recently, free vascularized fibular grafts have been used as an alternative in some cases. Here, we report the advantages of, and issues related to reconstruction using free vascularized fibular grafts observed at Tokyo Dental College Chiba Hospital. Eight patients undergoing mandibular reconstruction using free vascularized fibular grafts between January 2003 and January 2017 were investigated. Of these, 6 were men, and 2 were women. Age ranged from 38 to 74 years (average, 54 years). Primary diseases comprised malignant tumor in 3 patients, benign tumor in 3, and radiation osteomyelitis of the mandible in 2. The defects were classified as follows according to the CAT system (Condylar Head, Mandibular Angle, Mental Tubercle): 3 cases of Body, 2 of AT, and 1 case each of TT, ATTA, and CATT. The resection range of the mandible was 5-16 cm (average, 10 cm). The single barrel technique was used in 7 cases, and the double barrel technique in 1. In terms of the flap survival ratio, complete engraftment was achieved in 6 out of the 8 cases. Two cases of radiation osteomyelitis of the mandible, with necrosis caused by vascular breakdown after wound infection, were observed, however. While the advantages of mandibular reconstruction by this method include comparatively safe conditions and functional recovery, there were also some problems. It was inappropriate for cases of radiation osteomyelitis of the mandible; those where anti-inflammatory therapy was ineffective; and those where greater resection of the soft tissue was required. Further study is needed to clarify the criteria for selecting this procedure.
髂骨块状移植是下颌骨切除术后重建最常用的生物材料。然而,其使用存在一些缺点,包括可获取的骨量有限,以及随后髂骨负担的增加。因此,近年来,游离带血管腓骨移植在某些情况下被用作替代方法。在此,我们报告东京齿科大学千叶医院观察到的游离带血管腓骨移植重建的优点及相关问题。对2003年1月至2017年1月期间接受游离带血管腓骨移植进行下颌骨重建的8例患者进行了调查。其中,男性6例,女性2例。年龄范围为38至74岁(平均54岁)。原发性疾病包括3例恶性肿瘤、3例良性肿瘤和2例下颌骨放射性骨髓炎。根据CAT系统(髁突头、下颌角、颏结节),缺损分类如下:体部3例,角前部2例,颏结节、角前体部和髁突体部各1例。下颌骨切除范围为5 - 16 cm(平均10 cm)。7例采用单骨段技术,1例采用双骨段技术。在皮瓣存活率方面,8例中有6例完全植入。然而,观察到2例下颌骨放射性骨髓炎,因伤口感染后血管破裂导致坏死。虽然这种方法进行下颌骨重建的优点包括条件相对安全和功能恢复,但也存在一些问题。它不适用于下颌骨放射性骨髓炎病例;抗炎治疗无效的病例;以及需要更大范围切除软组织的病例。需要进一步研究以明确选择该手术的标准。