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一项关于护理院痴呆患者行为和心理症状的非药物干预的系统评价:从工效学的角度。

A systematic review of non-pharmacological interventions for BPSD in nursing home residents with dementia: from a perspective of ergonomics.

机构信息

Faculty of Industrial Design Engineering, Delft University of Technology, Delft, the Netherlands.

Section of Geriatric Medicine, Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.

出版信息

Int Psychogeriatr. 2019 Aug;31(8):1137-1149. doi: 10.1017/S1041610218001679.

Abstract

BACKGROUND

Non-pharmacological interventions for Behavioral and Psychological Symptoms of Dementia (BPSD) have been developed; however, a systematic review on the effectiveness of this type of intervention from a perspective of ergonomics is lacking. According to ergonomics, the capabilities of Persons with Dementia (PwD) should be considered in the interventions for the outcomes to be reliable. We aimed to systematically review the non-pharmacological interventions for BPSD in nursing home residents with an additional assessment criterion based on ergonomics, specifically, capability consideration.

METHODS

The electronic databases MEDLINE, EMBASE, and PsycINFO were searched for non-pharmacological interventions treating BPSD in nursing homes. The interventions were categorized according to the capabilities of PwD required to participate. Study quality was assessed by National Health and Medical Research Council (NHMRC) evidence hierarchy and the capability consideration.

RESULTS

Sixty-four clinical trials met the inclusion criteria; 41 trials reported a significant reduction in at least one BPSD symptom; 20 trials reported no significant reduction in BPSD symptoms; three trials reported adverse effects after the intervention. Interventions were categorized into sensory-, cognition-, and movement-oriented. Capabilities of PwD were not considered in 28 trials, especially for sensory capabilities.

CONCLUSIONS

The majority of the clinical trials reported a significant reduction in BPSD. The quality of evidence for nonpharmacological interventions in these trials is low due to the lack of capability consideration, data inhomogeneity, and inadequate study design and reporting. Future studies should focus on improving the quality of evidence by including capability consideration and examining if a relationship between capability consideration and effectiveness of non-pharmacological interventions exists.

摘要

背景

已经开发出针对痴呆行为和心理症状(BPSD)的非药物干预措施;然而,从工效学角度对这种干预措施的有效性进行系统评价还很缺乏。根据工效学,在干预措施中应考虑痴呆症患者(PwD)的能力,才能使结果可靠。我们旨在系统地评价针对疗养院居民 BPSD 的非药物干预措施,并增加基于工效学的额外评估标准,特别是考虑能力。

方法

检索 MEDLINE、EMBASE 和 PsycINFO 电子数据库,以寻找针对疗养院中 BPSD 的非药物干预措施。根据参与所需的 PwD 能力对干预措施进行分类。研究质量由澳大利亚国家卫生与医学研究委员会(NHMRC)证据等级和能力考虑进行评估。

结果

64 项临床试验符合纳入标准;41 项试验报告称至少有一种 BPSD 症状显著减轻;20 项试验报告称 BPSD 症状没有显著减轻;三项试验报告干预后出现不良反应。干预措施分为感觉、认知和运动导向。28 项试验未考虑 PwD 的能力,尤其是感觉能力。

结论

大多数临床试验报告 BPSD 显著减轻。由于缺乏能力考虑、数据异质性以及研究设计和报告不充分,这些试验中非药物干预措施的证据质量较低。未来的研究应侧重于通过纳入能力考虑来提高证据质量,并研究能力考虑与非药物干预措施有效性之间是否存在关系。

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