Emerg Infect Dis. 2018 Nov;24(11):2021-2028. doi: 10.3201/eid2411.170820.
We estimated numbers of hospitalizations for norovirus gastroenteritis (NGE) and associated medical costs in Germany, where norovirus testing is high because reimbursement is affected. We extracted aggregate data for patients hospitalized with a primary or secondary code from the International Classification of Diseases, 10th Revision (ICD-10), NGE diagnosis during 2007-2012 from the German Federal Statistics Office. We assessed reliability of the coding system in patient records from a large academic hospital. Approximately 53,000-90,000 NGE hospitalizations occurred annually in Germany (21,000-33,000 with primary and 32,000-57,000 with secondary ICD-10-coded NGE diagnoses). Rates of hospitalization with NGE as primary diagnosis were highest in children <2 years of age; rates of hospitalization with NGE as secondary diagnosis were highest in adults >85 years of age. The average annual reimbursed direct medical cost of NGE hospitalizations was €31-43 million. Among patients with a NGE ICD-10 code, 87.6% had positive norovirus laboratory results.
我们估计了德国诺如病毒肠胃炎（NGE）的住院人数和相关医疗费用，因为报销受到影响，德国的诺如病毒检测率很高。我们从德国联邦统计局提取了 2007 年至 2012 年期间，国际疾病分类第 10 版（ICD-10）中以初级或二级代码诊断为 NGE 的住院患者的汇总数据。我们评估了大型学术医院患者记录中编码系统的可靠性。德国每年约有 53,000-90,000 例 NGE 住院病例（初级诊断为 21,000-33,000 例，二级 ICD-10 编码为 32,000-57,000 例）。以 NGE 为主要诊断的住院率在<2 岁的儿童中最高；以 NGE 为次要诊断的住院率在>85 岁的成年人中最高。NGE 住院治疗的年平均报销直接医疗费用为 3100 万至 4300 万欧元。在有 NGE ICD-10 编码的患者中，87.6%的患者诺如病毒检测结果呈阳性。
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