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采用光动力疗法治疗局限性海绵状牙龈炎增生的保守方法:病例报告及文献综述

A Conservative Approach for Localized Spongiotic Gingivitis Hyperplasia Using Photodynamic Therapy: A Case Report and Review of the Literature.

作者信息

Vieira Danielle Leal, Leite André Ferreira, de Souza Figueiredo Paulo Tadeu, Vianna Leonora Maciel, Moreira-Mesquita Carla Ruffeil, de Melo Nilce Santos

机构信息

1 Department of Dentistry, Faculty of Health Sciences, University of Brasília , Brasília, Brazil .

2 Department of Pathology, Pathological Anatomy Center, University Hospital of Brasilia, University of Brasília , Brasília, Brazil .

出版信息

Photomed Laser Surg. 2018 Oct 18. doi: 10.1089/pho.2018.4454.

Abstract

OBJECTIVE

To describe a clinical case of successful conservative management of Localized Juvenile Spongiotic Gingivitis Hyperplasia (LJSGH) using photodynamic therapy (PDT) and reviews the current literature on this pathology.

BACKGROUND DATA

LJSGH is a recently described rare disease with controversial treatment results. As of today, 13 publications report surgical treatment approaches. The use of CO laser and cryotherapy was reported only in one study. The use of PDT was not previously reported.

PATIENTS AND METHODS

A 9-year-old male patient was referred to our institution with the chief complaint of asymptomatic "inflamed gingiva" starting 1 year before. Clinical examination revealed an erythematous line accompanying the gingival contour, with a certain degree of hyperplasia. The diagnosis of LJSGH was performed based on clinical features and later confirmed histopathologically. A novel approach using PDT was then proposed. The photosensitizer was methylene blue, and a semiconductor laser diode was used.

RESULTS

One week after starting PDT, gingival hyperplasia was partially reduced. Immediately after the end of treatment, a significant reduction of gingival hyperplasia was observed. PDT proved to be safe, quick and painless, with no esthetic harm.

CONCLUSIONS

This case illustrates the benefit of a more conservative approach as opposed to surgical procedure, with good clinical response and decreased morbidity over a 2-year follow-up period.

摘要

目的

描述一例采用光动力疗法(PDT)成功保守治疗局限性青少年海绵状龈炎增生(LJSGH)的临床病例,并回顾有关该病理的当前文献。

背景资料

LJSGH是一种最近描述的罕见疾病,治疗结果存在争议。截至目前,有13篇出版物报道了手术治疗方法。仅在一项研究中报道了使用CO激光和冷冻疗法。以前未报道过使用PDT。

患者和方法

一名9岁男性患者因1年前开始出现无症状的“牙龈发炎”主诉转诊至我院。临床检查发现牙龈轮廓有一条红斑线,伴有一定程度的增生。根据临床特征诊断为LJSGH,随后经组织病理学证实。然后提出了一种使用PDT的新方法。光敏剂为亚甲蓝,并使用了半导体激光二极管。

结果

开始PDT治疗一周后,牙龈增生部分减轻。治疗结束后立即观察到牙龈增生明显减轻。PDT被证明是安全、快速且无痛的,对美观没有损害。

结论

该病例说明了与手术方法相比采用更保守方法的益处,在2年的随访期内具有良好的临床反应且发病率降低。

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