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在特定合并症背景下,卢布林人群的内膜中层复合体厚度与颈动脉粥样硬化斑块形成情况

Intima-media complex thickness and carotid atherosclerotic plaque formation in Lublin's population in the context of selected comorbidities.

作者信息

Słomka Tomasz, Drelich-Zbroja Anna, Jarząbek Magdalena, Szczerbo-Trojanowska Małgorzata

机构信息

Department of Information Technology and Medical Statistics, Medical University of Lublin, Poland.

Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Poland.

出版信息

J Ultrason. 2018;18(73):133-139. doi: 10.15557/JoU.2018.0019.

Abstract

INTRODUCTION

Atherosclerosis (arteriosclerosis) is a chronic arterial disease of the arteries with chronic inflammatory. The pathology of atherosclerosis is complex, and the atherosclerotic process is multi-factorial, not fully understood. Risk factors of atherosclerotic lesions may include: lipid disorders, hypertension or diabetes. One of the diagnostic methods of discovering atherosclerosis covers the assessment of the intima-media complex thickness by Doppler ultrasonography.

AIM

The aim of this report was an evaluation of the relationships between intima-media complex thickness in the right and left carotid arteries and the occurrence of atheromatous plaque in the Lublin population with respect to three possible concomitant medical conditions, mentioned above.

MATERIAL AND METHODS

A group of 121 subjects was included into the study, all of the participants being residential inhabitants of the Lublin Voivodship. All the participating patients were requested to fill in a questionnaire. After that, the patients were submitted to Doppler sonography concentrated on intima-media complex thickness evaluation. The occurrence of atheromatous plaque was also assessed in obtained sonographic images.

RESULTS

There were statistically significant differences for the intima-media complex thickness and for the atheromatous plaque according to all of the reported diseases: hypocholesterolaemia, hypertension and diabetes. Conclusions: The present study confirms that there is a relationship between the thickness of the intima-media complex in the right and left carotid arteries as well as the occurrence of the atherosclerotic plaque regarding the coexistence of specific disease entities in the subjects of the Lublin population.

摘要

引言

动脉粥样硬化是一种伴有慢性炎症的慢性动脉疾病。动脉粥样硬化的病理过程复杂,其发病过程受多种因素影响,目前尚未完全明确。动脉粥样硬化病变的危险因素可能包括:脂质紊乱、高血压或糖尿病。发现动脉粥样硬化的诊断方法之一是通过多普勒超声评估内膜中层复合体厚度。

目的

本报告旨在评估卢布林地区人群左右颈动脉内膜中层复合体厚度与动脉粥样斑块的发生之间的关系,同时考虑上述三种可能并存的疾病情况。

材料与方法

本研究纳入了121名受试者,所有参与者均为卢布林省的居民。所有参与患者均被要求填写一份问卷。之后,对患者进行集中于内膜中层复合体厚度评估的多普勒超声检查。同时,在获得的超声图像中评估动脉粥样斑块的发生情况。

结果

根据所有报告的疾病(低胆固醇血症、高血压和糖尿病),内膜中层复合体厚度和动脉粥样斑块存在统计学显著差异。

结论

本研究证实,在卢布林地区人群中,左右颈动脉内膜中层复合体厚度与动脉粥样硬化斑块的发生之间存在关联,且与特定疾病实体的共存有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4167/6440505/cb0684eea1b7/jou-18-133-g001.jpg

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