Paris A, Clerc M, Peyramond D, Cochat N, Barbe G, Nsiangani N, Cochat P, Souillet G, Philippe N
Pediatrie. 1986 Dec;41(8):653-6.
Authors report a new case of acute erythroblastopenia linked to a parvovirus B 19 infection by a 10 years old boy suffering from an hereditary spherocytosis. Aurillac antigen or parvovirus B 19 is one of the smallest virus to be known. It has been well demonstrated in vitro that the virus inhibits especially erythropoiesis but mechanism remains unclear. Systematic vaccination of all children at risk with congenital or acquired chronic haemolytic anaemia should be in the near future the best prophylaxis of parvovirus B 19 infections.
作者报告了一例新的急性成红细胞减少症病例，该病例与一名患有遗传性球形红细胞增多症的10岁男孩感染细小病毒B19有关。奥里拉克抗原或细小病毒B19是已知最小的病毒之一。体外实验已充分证明该病毒尤其会抑制红细胞生成，但其机制仍不清楚。在不久的将来，对所有有先天性或后天性慢性溶血性贫血风险的儿童进行系统性疫苗接种应是预防细小病毒B19感染的最佳措施。
