Mohapatra Madhusmita Mohanty, Rajaram Manju, Mallick Archana
Department of Pulmonary Medicine, JIPMER, Pondicherry, India.
Open Access Maced J Med Sci. 2018 Sep 23;6(9):1642-1646. doi: 10.3889/oamjms.2018.374. eCollection 2018 Sep 25.
The incidence of lung abscess acquired in the community is unknown, but this is a common clinical problem encountered in developing countries. The incidence of lung abscess was high in the pre-antibiotic era but the advent of susceptible antibiotics it has reduced with an equal fall in mortality to 8.7%. With the emerging antibiotic resistance and change in the trends of bacteriological profile causing lung abscess, it is the need of time to reevaluate lung abscess.
The study aimed to determine the clinical, radiological and bacteriological profile of lung abscess.
The study was a non-randomized prospective observational study conducted in the department of pulmonary medicine for 18 months. In the study, patients > 15 years of age with clinical features of lung abscess were recruited and were subjected to chest X-ray, routine blood test. Sputum gram stain and culture, as well as antibiotic sensitivity according to the organism, were evaluated. Reports of all investigations along with patient characteristics and risk factors were analysed statistically using SPSS 20.0.
Forty-six cases of lung abscess were included, and the majority of patients were found to be adults with a mean age of 42.9 years with a male to female ratio of 6.6:1. The most common predisposing factor was an unhygienic oral cavity in 28% of cases with alcohol ingestion being the most important risk factor in 22% of cases. The most common organism found in lung abscess cases was , and they were sensitive to ceftazidime.
Our study shows that should be considered an important pathogen in community-acquired lung abscesses.
社区获得性肺脓肿的发病率尚不清楚,但这是发展中国家常见的临床问题。在抗生素时代之前,肺脓肿的发病率很高,但随着敏感抗生素的出现,其发病率有所下降,死亡率也降至8.7%。随着抗生素耐药性的出现以及导致肺脓肿的细菌学特征趋势的变化,重新评估肺脓肿已迫在眉睫。
本研究旨在确定肺脓肿的临床、放射学和细菌学特征。
本研究是在肺病科进行的一项为期18个月的非随机前瞻性观察研究。在研究中,招募了年龄大于15岁且具有肺脓肿临床特征的患者,并对其进行胸部X光检查、血常规检查。评估痰革兰氏染色和培养情况,以及根据病原体进行的抗生素敏感性测试。使用SPSS 20.0对所有检查报告以及患者特征和危险因素进行统计学分析。
纳入了46例肺脓肿病例,发现大多数患者为成年人,平均年龄为42.9岁,男女比例为6.6:1。最常见的诱发因素是口腔卫生不良,在28%的病例中出现,饮酒是22%病例中最重要的危险因素。肺脓肿病例中最常见的病原体是 ,它们对头孢他啶敏感。
我们的研究表明, 应被视为社区获得性肺脓肿的重要病原体。