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降钙素对大鼠肝脏颗粒糖原中磷酸化酶a及葡萄糖-6-磷酸酶活性的影响。

Effect of calcitonin on phosphorylase a and glucose-6-phosphatase activities in the hepatic particulate glycogen of rats.

作者信息

Coprean D, Orbai P, Gozariu L, Danci D

出版信息

Endocrinologie. 1987 Jan-Mar;25(1):15-9.

PMID:3033811
Abstract

A single dose of calcitonin (CT) (70 mU MRC/100 g body weight) was administered in 50 and 90 days old male Wistar rats. In both ages CT determined a rise of Phosphorylase a and glucose-6-phosphatase activity as well as an increased calcium accumulation at the level of liver particulate glycogen. In the rats receiving CT glycemia increased and the liver glycogen content decreased. With the exception of liver glycogen the other metabolic parameters studied were modified at the two ages in the same manner under the influence of the same dose of CT.

摘要

对50日龄和90日龄的雄性Wistar大鼠给予单剂量降钙素(CT)(70 mU MRC/100 g体重)。在这两个年龄段,CT均使磷酸化酶a和葡萄糖-6-磷酸酶活性升高,同时肝脏颗粒糖原水平的钙积累增加。接受CT的大鼠血糖升高,肝脏糖原含量降低。除肝糖原外,在相同剂量CT的影响下,所研究的其他代谢参数在两个年龄段均以相同方式发生改变。

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