Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, No. 325, Sec. 2, Cheng-Kung Road, Neihu District, Taipei, Taiwan, 11490, Republic of China.
Integrated Pain Management Center, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Muscle Nerve. 2019 Feb;59(2):174-180. doi: 10.1002/mus.26358. Epub 2018 Dec 4.
INTRODUCTION: In this study we explored the efficacy of nerve hydrodissection for mild-to-moderate carpal tunnel syndrome (CTS). METHODS: Thirty-four participants were randomly assigned to an intervention group or a control group. One 5-ml dose of normal saline was injected into the intracarpal and subcutaneous regions in subjects of both groups, respectively. The primary outcome measure was the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) score. Secondary outcomes were cross-sectional area of the median nerve and electrophysiological studies. Assessments were performed before the injection and at 1, 2, 3, and 6 months postintervention. RESULTS: Compared with the control group, the intervention group showed significantly greater improvement at the second and third posttreatment months according to BCTQ severity score and at all time-points for cross-sectional area of the median nerve (P < 0.01). DISCUSSION: Our study demonstrates the therapeutic effects of nerve hydrodissection for mild-to-moderate CTS. Muscle Nerve 59:174-180, 2019.
简介：本研究旨在探讨神经水分离术治疗轻中度腕管综合征（CTS）的疗效。
方法：34 名参与者被随机分配到干预组或对照组。两组受试者分别向腕管内和皮下区域注射 5ml 生理盐水。主要结局测量指标为波士顿腕管综合征问卷（BCTQ）评分。次要结局是正中神经的横截面积和电生理研究。在注射前和注射后 1、2、3 和 6 个月进行评估。
结果：与对照组相比，干预组在治疗后第 2 和第 3 个月的 BCTQ 严重程度评分以及所有时间点的正中神经横截面积方面均有显著改善（P < 0.01）。
讨论：我们的研究表明，神经水分离术治疗轻中度 CTS 具有治疗效果。肌肉神经 59：174-180，2019 年。
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