Ansari Mohammad Zeya, Tolstoy R, Jagadeeswaran G
Department of General Medicine, PSG IMS and R, Coimbatore, Tamil Nadu.
J Assoc Physicians India. 2018 Mar;66(3):86-7.
Thrombocytopenia is a common complication in patients with chronic liver disease and is multi-factorial. It complicates the management and worsens the prognosis. Treatment options are costly and include platelet transfusion, splenectomy, splenic artery embolization, TIPPS and thrombopoietin (TPO) agonists. Here we are presenting a patient with decompensated liver disease with known chronic alcoholism and profound thrombocytopenia despite multiple platelet transfusions. On further work up we found a coexistent autoimmune etiology. Thrombocytopenia promptly responded to steroids, a cost effective option.
血小板减少症是慢性肝病患者常见的并发症，且病因是多方面的。它使治疗变得复杂并使预后恶化。治疗选择成本高昂，包括血小板输注、脾切除术、脾动脉栓塞、经颈静脉肝内门体分流术（TIPPS）和血小板生成素（TPO）激动剂。在此，我们报告一名失代偿性肝病患者，其有慢性酒精中毒史，尽管多次输注血小板仍有严重血小板减少症。进一步检查发现存在自身免疫性病因。血小板减少症对类固醇治疗迅速起效，这是一种经济有效的选择。
