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戊型肝炎病毒相关的急性脑炎型帕金森综合征

Hepatitis E Virus-Associated Acute Encephalitic Parkinsonism.

作者信息

Pasha Shaik Afsar, Pasha Shaik Arif, Suhasini T, Rao D Ankamma

机构信息

Associate Professor, Department of Neurology.

Professor, Department of Critical Care Medicine.

出版信息

J Assoc Physicians India. 2018 Mar;66(3):92-3.

PMID:30341882
Abstract

Hepatitis E virus (HEV) is a common infection worldwide and is an emerging infectious disease in the developed countries. The unique characteristics of HEV is that it displays different epidemiological and clinical characteristics between developing and developed countries. Neurological disorders are emerging extra hepatic manifestations of both acute and chronic Hepatitis E virus infection. We report a 17 year old sportsman presenting with acute encephalitic Parkinsonism concurrent with acute hepatitis. Serology was positive for Hepatitis E virus (HEV) and HEV RNA was confirmed. Patient improved completely with symptomatic treatment. We suggest offering diagnostic testing for Hepatitis E virus in patients of neurological disorders with concurrent liver impairment.

摘要

戊型肝炎病毒(HEV)在全球范围内是一种常见感染,在发达国家是一种新发传染病。HEV的独特之处在于,它在发展中国家和发达国家表现出不同的流行病学和临床特征。神经功能障碍是急性和慢性戊型肝炎病毒感染新出现的肝外表现。我们报告一名17岁的运动员,患有急性脑炎型帕金森症并伴有急性肝炎。戊型肝炎病毒(HEV)血清学检测呈阳性,且HEV RNA得到确认。患者经对症治疗后完全康复。我们建议,对并发肝功能损害的神经功能障碍患者进行戊型肝炎病毒诊断检测。

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