Mario Lara C, Morais Maiara P, Borghesi Jessica, Favaron Phelipe O, Oliveira Franceliusa D, Anunciação Adriana R A, Agopian Rafael G, Gomes Samirah A, Miglino Maria A
Sector of Wild and Domestic Animals Anatomy, College of Veterinary Medicine and Animal Science of the University of Sao Paulo FMVZ/USP, São Paulo, Brazil.
Sector of Wild and Domestic Animals Anatomy, College of Veterinary Medicine and Animal Science of the University Santo Amaro University UNISA, São Paulo, Brazil.
Microsc Res Tech. 2018 Nov;81(11):1286-1294. doi: 10.1002/jemt.23135. Epub 2018 Oct 20.
The embryonic origin of the urogenital system came from the intermediate mesoderm. Kidney development involves three successive renal systems with a fast chronological overlap: the pronephro, the mesonephro, and the metanephro. Due to the lack of specific knowledge about this system in cats the present work aimed to describe their urinary organs development, focusing on the structures seen in pronephro, mesonephro, and metanephro during the embryonic and fetal stages of development. The techniques used in this study were: light microscopy, immunohistochemistry, scanning electron microscopy, and transmission electron microscopy. For that, embryos and fetuses from 12 pregnant mixed-breed domestic cats in different gestational stages were used to describe the proposed organs. The pronephro is present at early stages of embryonary development in embryos from 15 to 19 days with the presence of pronephro's corpuscles, ducts and tubules. The mesonephro is found, in general, between days 17 and 37, and contains mesonephric ducts, mesonephric tubules, and glomeruli. The metanephro is seen since 21 days of pregnancy with the presence of glomeruli, proximal and distal contorted tubules and at day 37, the cortex-medullary region is already differentiated. The evaluation of these structures enhances the knowledge about embryology of the urinary system in cats, aiding a better anatomical understanding of the system in the specie allowing the correlation with other species.
泌尿生殖系统的胚胎起源来自中间中胚层。肾脏发育涉及三个相继出现且在时间上快速重叠的肾脏系统：前肾、中肾和后肾。由于缺乏关于猫科动物该系统的具体知识，本研究旨在描述其泌尿器官的发育，重点关注胚胎和胎儿发育阶段在前肾、中肾和后肾中观察到的结构。本研究使用的技术包括：光学显微镜、免疫组织化学、扫描电子显微镜和透射电子显微镜。为此，使用了来自12只处于不同妊娠阶段的怀孕混种家猫的胚胎和胎儿来描述所提议的器官。前肾存在于胚胎发育的早期阶段，即15至19天的胚胎中，有前肾小体、导管和小管。一般来说，中肾在第17至37天之间出现，包含中肾管、中肾小管和肾小球。后肾自妊娠21天起可见，有肾小球、近端和远端曲管，在第37天，皮质 - 髓质区域已分化。对这些结构的评估增进了对猫科动物泌尿系统胚胎学的了解，有助于更好地从解剖学角度理解该物种的这个系统，并与其他物种进行关联。
