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脐带组织和胎便可能无法等同用于确认宫内物质暴露。

Umbilical Cord Tissue and Meconium May Not Be Equivalent for Confirming in Utero Substance Exposure.

机构信息

Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN.

Enterprise Analytics, Vanderbilt University Medical Center, Nashville, TN.

出版信息

J Pediatr. 2019 Feb;205:277-280. doi: 10.1016/j.jpeds.2018.09.046. Epub 2018 Oct 17.

Abstract

In a retrospective study of 501 neonates with potential in utero substance exposure, the drug detection performance of a commercially available umbilical cord tissue toxicology test was evaluated against a commercially available gold standard meconium toxicology test. Drugs detected in paired meconium and umbilical cord tissue samples were often discordant.

摘要

在一项对 501 例有潜在宫内物质暴露风险的新生儿进行的回顾性研究中,评估了一种市售的脐带组织毒理学检测与一种市售的金标准胎粪毒理学检测的药物检测性能。在配对的胎粪和脐带组织样本中检测到的药物往往不一致。

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